Bacterial adhesion (inhibition) · Streptococcus mutans (in vitro cultures and biofilms)
Grape seed extract inhibits S. mutans adhesion to hydroxyapatite in vitro (2 studies; ungraded).
1 finding from 1 review
Bacterial adhesion or initial colonization · Streptococcus mutans (in vitro cultures and biofilms)
No meta-analysis was conducted; three included studies reported reduced adhesion or initial colonization with cranberry extract or fractions.
1 finding from 1 review
no estimate extracted
3 studies
GRADE not reported
Bacterial adhesion (inhibition) · Streptococcus mutans (in vitro cultures and biofilms)
Cranberry extract inhibits S. mutans adhesion / initial colonization in vitro (3 studies; ungraded).
1 finding from 1 review
Bacterial adhesion · Streptococcus mutans (in vitro cultures and biofilms)
No meta-analysis was conducted; two included studies reported reduced Streptococcus mutans adhesion with grape seed extract or fractions.
1 finding from 1 review
no estimate extracted
2 studies
GRADE not reported
Impaired OHRQoL measured with CPQ 11-14 (quantitative synthesis / meta-analysis) · Adolescents (10-19 years)
Malocclusion (DAI) probably increases the prevalence of impaired OHRQoL (CPQ 11-14) by about 15% in adolescents (RR/PR 1.15, 95% CI 1.12-1.18; moderate certainty).
1 finding from 1 review
Salivary flow rate · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth
Across 19 studies the effect of gum chewing on stimulated and/or unstimulated salivary flow rate was mixed (9 positive, 10 no effect); this broad outcome was not meta-analyzed.
1 finding from 1 review
The effect of gum chewing on xerostomia and salivary flow rate in elderly and medically compromised subjects: a… 2023 All outcomesVarious (single session to 12 months) · Haemodialysis units, elderly / geriatric care, cancer and palliative care, and xerostomia / hyposalivation clinics (studies from multiple countries)
Narrative vote-count: of 19 studies measuring stimulated and/or unstimulated saliva flow rate, 9 found a positive effect of gum chewing [17,18,22,24,27,35,36,38,39] and 10 detected no effect…
19 studies
GRADE not reported
Survival of retainers (failure/how many failed) · People who had received fixed appliance orthodontic treatment
It is very uncertain whether hawley removable retainer changes survival of retainers (failure, upper and lower arches) compared with clear plastic removable retainer (very low certainty).
1 finding from 1 review
Patient satisfaction: comfort (VAS, upper and lower arches) · People who had received fixed appliance orthodontic treatment
The review found no eligible studies for this question.
1 finding from 1 review
Poor oral health-related quality of life (OHRQoL) · Adolescents (10-19 years)
Malocclusions probably have a negative effect on OHRQoL in adolescents, after adjustment for confounders (moderate certainty).
1 finding from 1 review
Impaired OHRQoL, qualitative synthesis: relative effect not estimable across the 13 studies (13,864 participants); moderate quality of evidence (GRADE).
13 studies · 13864 participants
Moderate
Reduction in level of contamination in aerosols (CFU per cubic feet/min/patient) using Reyniers slit sampler 30 inches (76 cm) from floor · People undergoing aerosol-generating procedures (AGPs) in a dental setting
It is very uncertain whether laminar air flow with HEPA filter changes reduction in level of contamination in aerosols (CFU per cubic… compared with without laminar flow or filter (very low certainty).
1 finding from 1 review
Reduction in level of contamination in aerosols (CFU) during restorative procedures at participant's chest · People undergoing aerosol-generating procedures (AGPs) in a dental setting
It is very uncertain whether rubber dam + HVE changes reduction in level of contamination in aerosols (CFU) during… compared with cotton roll + HVE (very low certainty).
1 finding from 1 review
Need for anaesthesia · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)
Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) led to lower need for anaesthesia compared with conventional mechanical caries removal (standard drill; handpiece…; GRADE not reported.
2 findings from 1 review
Requirement for general anaesthesia due to dental procedures for caries · general population
The review found no eligible studies for this question.
1 finding from 1 review
Patient-reported altered sensation (spontaneous or evoked: anaesthesia/paraesthesia/dysaesthesia/hyperalgesia/allodynia) · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve
It is very uncertain whether low-level laser therapy (photon-plus GaAlAs diode laser; 70 mW… changes patient-reported altered sensation (spontaneous or evoked:… compared with placebo (sham) laser therapy (very low certainty).
2 findings from 1 review
Prosthesis failure · Patients undergoing lateral-window maxillary sinus lift
Resorbable barrier (membrane) to seal the lateral window showed no clear difference in prosthesis failure compared with no membrane to seal the lateral window; GRADE not reported.
1 finding from 1 review
Prosthesis failure · Patients undergoing crestal maxillary sinus lift
1 finding from 1 review
Checchi 2010 (split-mouth, N = 12): no prosthetic failures in either group.
1 study · 12 participants
GRADE not reported
Prosthesis failure · Patients undergoing lateral-window maxillary sinus lift
1 finding from 1 review
Rickert 2013 (split-mouth, N = 36): no prosthesis failures in either group.
1 study · 36 participants
GRADE not reported
Prosthesis failure · Patients with 3 to 6 mm of residual bone height at the sinus floor
One-stage crestal-approach sinus lift with autogenous bone and 8 mm… showed no clear difference in prosthesis failure compared with lateral-window sinus lift with 50% autogenous bone/50% Bio-Oss and…; GRADE not reported.
1 finding from 1 review
Prosthesis failure · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height)
Sinus lift with bone graft (granular Bio-Oss) showed no clear difference in prosthesis failure compared with sinus lift without bone graft (Inion resorbable rigid barrier…; GRADE not reported.
1 finding from 1 review
Prosthesis failure · Patients with 2 to 7 mm of residual alveolar bone height in the edentulous maxillary sinus floor
One-stage lateral sinus lift with monocortical autogenous bone… showed no clear difference in prosthesis failure compared with two-stage lateral sinus lift with autogenous particulate bone (iliac…; GRADE not reported.
1 finding from 1 review