Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

16 questions · 17 findings · 7 reviews · Musculoskeletal

No studies found 5 · 29.4%GRADE not reported 1 · 5.9%Very low 3 · 17.6%Low 8 · 47.1%Moderate 0 · 0%High 0 · 0%

Prefabricated foot orthoses vs shoes

Withdrawals due to adverse events · children with juvenile idiopathic arthritis and flat feet

Prefabricated foot orthoses showed no clear difference in withdrawal due to adverse events compared with shoes; GRADE not reported.

1 finding from 1 review

Skim milk enriched with GMP/G600 vs skim milk & lactose powder

Withdrawals due to adverse events · people with chronic gout

Skim milk enriched with GMP/G600 showed no clear difference in study withdrawals due to adverse events compared with skim milk, plus lactose powder (low certainty).

2 findings from 2 reviews · compare the 2 reviews

Custom foot orthoses vs shoes

Withdrawals due to adverse events · children with juvenile idiopathic arthritis and flat feet

Custom foot orthoses showed no clear difference in withdrawal due to adverse events compared with shoes (low certainty).

1 finding from 1 review

Benzbromarone vs probenecid

Withdrawals due to adverse events · people with chronic gout

Benzbromarone may leads to lower withdrawal due to adverse events compared with probenecid (low certainty).

1 finding from 1 review

Benzbromarone vs allopurinol

Withdrawals due to adverse events · people with chronic gout

Benzbromarone showed no clear difference in withdrawal due to adverse events compared with allopurinol (low certainty).

1 finding from 1 review