Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

128 questions · 130 findings · 92 reviews

No studies found 12 · 9.2%GRADE not reported 10 · 7.7%Very low 36 · 27.7%Low 46 · 35.4%Moderate 18 · 13.8%High 8 · 6.2%

Probiotics vs placebo

Withdrawals due to adverse events · children with chronic constipation without a physical explanation

Probiotic showed no clear difference in withdrawals due to adverse events compared with placebo (low certainty).

1 finding from 1 review

Belimumab 10 mg/kg vs placebo

Withdrawals due to adverse events · people with active systemic lupus erythematosus (but not active nephritis or active central nervous system involvement)

Belimumab 10 mg/kg showed no clear difference in withdrawals due to adverse events compared with placebo (moderate certainty).

1 finding from 1 review

All doses of cerivastatin vs placebo

Withdrawals due to adverse events · participants with normal or abnormal lipid profiles

It is very uncertain whether all doses of cerivastatin changes withdrawals due to adverse events compared with placebo (very low certainty).

1 finding from 1 review

Adalimumab vs placebo

Withdrawals due to adverse events · Participants with Crohn's disease in remission

Adalimumab probably leads to lower withdrawals due to adverse events compared with placebo (moderate certainty).

1 finding from 1 review