Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

24 questions · 24 findings · 11 reviews

No studies found 5 · 20.8%GRADE not reported 9 · 37.5%Very low 8 · 33.3%Low 2 · 8.3%Moderate 0 · 0%High 0 · 0%

Probiotics vs placebo

Adverse events (serious adverse reaction and adverse reaction) · children and adults with CF

Probiotics showed no clear difference in adverse events (serious adverse reaction and adverse reaction) compared with placebo (low certainty).

1 finding from 1 review

Probiotics used as adjuvants to conventional antifungal drugs vs conventional antifungal drugs

Rate of serious adverse events · non‐pregnant women with vulvovaginal candidiasis

Probiotics used as adjuvants to conventional antifungal drugs showed no clear difference in rate of serious adverse events compared with conventional antifungal drugs (low certainty).

1 finding from 1 review