Question · asked by 1 review
Probiotics vs placebo: Adverse events (serious adverse reaction and adverse reaction)
- Population
- children and adults with CF
- Intervention
- Probiotics
- Comparison
- placebo
- Outcome
- Adverse events (serious adverse reaction and adverse reaction)
Probiotics showed no clear difference in adverse events (serious adverse reaction and adverse reaction) compared with placebo (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Probiotics vs placebo Adverse events (serious adverse reaction and adverse reaction) · children and adults with CF Probiotics showed no clear difference in adverse events (serious adverse reaction and adverse reaction) compared with placebo (low certainty). Probiotics for people with cystic fibrosis (2020) · Cochrane Headline outcomes only | RR 3 [0.49, 18.46] | 5 studies · 310 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Probiotics for people with cystic fibrosis 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.