What do systematic reviews say?

Pregabalin 300 mg or 600 mg vs placebo

• Pregabalin for neuropathic pain in adults 2019 · Cochrane Headline outcomes only
  no estimate extracted
  17 studies · 4112 participants
  High

Intervention not reported

• Zolmitriptan for acute migraine attacks in adults 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Moderate

Intervention not reported

The review found no eligible studies for this question.

• Ibuprofen with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Aspirin with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Diclofenac with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Naproxen 500 mg or 825 mg vs placebo

The review found no eligible studies for this question.

• Naproxen with or without an antiemetic for acute migraine headaches in adults 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

High‐dose corticosteroids vs moderate‐dose or no corticosteroids

High‐dose corticosteroids probably leads to higher serious adverse events compared with moderate‐dose or no corticosteroids (moderate certainty).

• Interventions for the treatment of metastatic extradural spinal cord compression in adults 2015 · Cochrane Headline outcomes only
  RR 8.02 [1.03, 62.37]
  2 studies · 77 participants
  Moderate

Sumatriptan 50 mg or 85 mg plus naproxen 500 mg vs placebo

The review found no eligible studies for this question.

• Sumatriptan plus naproxen for the treatment of acute migraine attacks in adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Single dose oral ibuprofen plus codeine for acute postoperative pain in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

• Single dose oral etoricoxib for acute postoperative pain in adults 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

Intervention not reported

• Single dose oral dexibuprofen [S(+)‐ibuprofen] for acute postoperative pain in adults 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Ketoprofen 50 mg vs placebo

• Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 688 participants
  Very low

Dexketoprofen 10 mg‐12.5 mg vs placebo

• Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 574 participants
  Very low

Dexketoprofen 20 mg or 25 mg vs placebo

• Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 1271 participants
  Very low

Ketoprofen 25 mg vs placebo

• Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 535 participants
  Very low

Dexketoprofen 25 mg plus tramadol 75 mg vs placebo

• Single fixed‐dose oral dexketoprofen plus tramadol for acute postoperative pain in adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 123 participants
  Very low