Cochrane · systematic review · CD008783
Diclofenac with or without an antiemetic for acute migraine headaches in adults
Derry, S, Rabbie, R, Moore, RA · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
4
No studies
2
Included studies
NR
No studies 2 · 33.3%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 16.7%Moderate 3 · 50%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: adults with migraine headache ‐ moderate or severe pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain‐free at 2 h | no estimate extracted | 2 studies · 1447 participants | Moderate Downgraded: publication bias |
Headache relief at 2 h | no estimate extracted | 2 studies · 1447 participants | Moderate Downgraded: publication bias |
Sustained pain‐free at 24 h | no estimate extracted | 2 studies · 1578 participants | Moderate Downgraded: publication bias |
Sustained headache relief at 24 h | no estimate extracted | NR | No studies |
At least one AE | no estimate extracted | 3 studies · 1075 participants | Low Downgraded: publication bias |
Serious AE | no estimate extracted | NR | No studies |