Cochrane · systematic review · CD010107
Single dose oral ibuprofen plus codeine for acute postoperative pain in adults
Derry, S, Karlin, SM, Moore, RA · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
2
No studies
2
Included studies
NR
No studies 2 · 50%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 25%High 1 · 25%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: adults with moderate or severe acute postoperative pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
At least 50% of maximum pain relief over 4 to 6 h | RR 4.1 [2.8, 5.9] | NR | High |
Participants with at least 1 adverse event | RR 1.2 [0.84, 1.7] | NR | Moderate |
Participants with a serious adverse event | no estimate extracted | NR | No studies |
Deaths | no estimate extracted | NR | No studies |