Findings

What do systematic reviews say?

35 questions · 35 findings · 22 reviews · Headline outcomes only

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No studies found 8 · 22.9%GRADE not reported 1 · 2.9%Very low 10 · 28.6%Low 9 · 25.7%Moderate 6 · 17.1%High 1 · 2.9%

Multi‐component intervention vs usual care or attention control

Health‐related quality of life · Older people living in the community

1 finding from 1 review

Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 391 participants
Low

Multi‐component intervention vs exercise

Health‐related quality of life · Older people living in the community

The review found no eligible studies for this question.

1 finding from 1 review

Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

SMP vs usual care

Quality of life measured on multiple scales (0 to 100; higher score = better quality of life) Postintervention: first assessment after end of treatment; no later than 3 months · patients with osteoarthritis

1 finding from 1 review

Self‐management education programmes for osteoarthritis 2014 · Cochrane Headline outcomes only
no estimate extracted
1383 participants
Moderate

Interventions designed to improve any type of continuity vs usual care

QoL · cancer patients

1 finding from 1 review

Interventions to improve continuity of care in the follow‐up of patients with cancer 2012 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 2622 participants
Very low

SMP vs information only

1 finding from 1 review

Self‐management education programmes for osteoarthritis 2014 · Cochrane Headline outcomes only
no estimate extracted
648 participants
Moderate

SMP vs non‐SMP intervention

1 finding from 1 review

Self‐management education programmes for osteoarthritis 2014 · Cochrane Headline outcomes only
no estimate extracted
226 participants
Moderate

Intervention not reported

Quality of life measured on multiple scales (0 to 100; higher score = better quality of life) Postintervention: first assessment after end of treatment; no later than 3 months · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain

1 finding from 1 review

Physical activity and education about physical activity for chronic musculoskeletal pain in children and adolescents 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 201 participants
Very low

Intervention not reported

Health‐related quality of life Multiple different outcome measures used EQ‐5D and EQ‐5D VAS (9 and 26 weeks) (Batterham 2014) SF‐36 PCS and MCS (8 and 26 weeks) (Elliott 2011) · adult survivors of critical illness

1 finding from 1 review

Exercise rehabilitation following intensive care unit discharge for recovery from critical illness 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2 participants
Very low

Intervention not reported

Global quality of life score Multiple measures used. WHO‐Five‐Wellbeing Index (Ledderer 2013) FACT‐G total score (Northouse 2007). Additional study (reported in comments section): SF20 subscales (Blanchard 1996). Higher scores indicate better QoL · informal caregivers of people affected by cancer

1 finding from 1 review

Psychosocial interventions for informal caregivers of people living with cancer 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 239 participants
Low

Intervention not reported

Global quality of life FLIC total score (Blanchard 1996), FACT‐G total score (Northouse 2007). Additional studies (reported in comments section): FACT‐B physical functioning subscale (Baucom 2009). EPIC multiple subscales and overall scores (Campb... · individuals with cancer (patients)

1 finding from 1 review

Psychosocial interventions for informal caregivers of people living with cancer 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 292 participants
Very low

Rituximab vs placebo

Quality of life · primary progressive multiple sclerosis

The review found no eligible studies for this question.

1 finding from 1 review

Rituximab for people with multiple sclerosis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Rituximab vs placebo

Quality of life · relapsing multiple sclerosis

The review found no eligible studies for this question.

1 finding from 1 review

Rituximab for people with multiple sclerosis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise vs control immediately post intervention

Quality of life · people with multiple sclerosis

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing falls in people with multiple sclerosis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life · newly diagnosed, transplant‐ineligible adults with symptomatic multiple myeloma

The review found no eligible studies for this question.

1 finding from 1 review

Multiple drug combinations of bortezomib, lenalidomide, and thalidomide for first‐line treatment in adults with… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Information provision vs (Optimised) usual care

Quality of life · people with multiple sclerosis

1 finding from 1 review

Information provision for people with multiple sclerosis 2018 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 671 participants
Low

Plerixafor vs placebo

Quality of life · People with haematopoietic stem cell mobilisation for autologous transplantation in malignant lymphoma or multiple myeloma

The review found no eligible studies for this question.

1 finding from 1 review

Additional plerixafor to granulocyte colony‐stimulating factors for haematopoietic stem cell mobilisation for… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Bortezomib vs no bortezomib

Health‐related quality of life · All patients with a diagnosis of multiple myeloma

1 finding from 1 review

Bortezomib for the treatment of multiple myeloma 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 717 participants
GRADE not reported

Decompressive surgery plus radiotherapy vs radiotherapy

Quality of life · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of metastatic extradural spinal cord compression in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Respiratory muscle training vs sham training or no training

Quality of Life (EQ‐5D VAS, score · people with multiple sclerosis

1 finding from 1 review

Respiratory muscle training for multiple sclerosis 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Low

WBRT with radiosensitisers (radiosen) vs WBRT

Quality of lifeNo. of participants: 271(2 RCTs) · patients with newly diagnosed multiple brain metastases

1 finding from 1 review

Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate