What do systematic reviews say?

Metformin 500 mg to 2550 mg per day vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Multimodal intervention (exercise plus other interventions) plus usual care vs usual care

• Exercise for cancer cachexia in adults 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Very low

Orthodontic treatment with appliances inducing stable, permanent orthodontic tooth movement (splints worn 8 to 12 weeks and surgical interventions excluded) vs Control: no treatment, placebo, or reassurance

The review found no eligible studies for this question.

• Orthodontics for treating temporomandibular joint (TMJ) disorders 2010 · Cochrane All outcomes

  At least 6 months after the intervention
  no estimate extracted
  0 studies
  No studies found

Brief admission to psychiatric hospital by self‐referral plus treatment as usual vs treatment

The review found no eligible studies for this question.

• Crisis interventions for adults with borderline personality disorder 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Chemotherapy (any regimen; added to, or compared with, locoregional treatment) vs Locoregional treatment and/or an alternative chemotherapy regimen

The review found no eligible studies for this question.

• Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy 2021 · Cochrane All outcomes
  Quality of life was a planned (protocol) outcome but no included trial provided usable quality-of-life data; the protocol was modified to report only survival/response outcomes.
  0 studies
  No studies found

Peer support vs alternative interventions

The review found no eligible studies for this question.

• Peer support interventions for parents and carers of children with complex needs 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CBT with therapist support vs fatigue information leaflet only

• Interventions for fatigue in inflammatory bowel disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 19 participants
  Very low

Telephone support vs non‐telephone support intervention

The review found no eligible studies for this question.

• Telephone interventions, delivered by healthcare professionals, for providing education and psychosocial support for… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Hyperbaric oxygen therapy plus standard care (surgery, antibiotics, oral rinse) vs Standard care alone (surgery, antibiotics, oral rinse)

• Interventions for treating bisphosphonate‐related osteonecrosis of the jaw (BRONJ) 2016 · Cochrane All outcomes

  Baseline and 6 months
  no estimate extracted
  1 study · 49 participants
  GRADE not reported

Laminectomy plus radiotherapy vs radiotherapy

The review found no eligible studies for this question.

• Interventions for the treatment of metastatic extradural spinal cord compression in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Decompressive surgery plus radiotherapy vs radiotherapy

The review found no eligible studies for this question.

• Interventions for the treatment of metastatic extradural spinal cord compression in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: Defibrotide vs no treatment

The review found no eligible studies for this question.

• Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem cell… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Low‐level laser therapy vs Placebo (sham) laser therapy

The review found no eligible studies for this question.

• Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
  Results: 'No studies reported on quality of life ...'. Not reported by the included laser trials.
  0 studies
  No studies found

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

The review found no eligible studies for this question.

• Interventions for managing relapse of the lower front teeth after orthodontic treatment 2013 · Cochrane All outcomes
  No RCTs met the inclusion criteria for this review. After deduplication, the electronic searching identified 527 publications; after reviewing the titles and abstracts, none focused on interventions to correct the…
  0 studies
  No studies found

Bee propolis (one 500 mg capsule per day) vs placebo

• Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes

  6 months (minimum)
  Patients in the propolis group self-reported a significant improvement in their quality of life (P=0.03), based on volunteered statements of self-reported improvement.
  1 study · 19 participants
  GRADE not reported

Intervention not reported

• Interventions for supporting informal caregivers of patients in the terminal phase of a disease 2011 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 631 participants
  Low

Summary of findings for cholinesterase inhibitors vs placebo

• Interventions for preventing falls in Parkinson's disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 121 participants
  Very low

Intervention not reported

The intervention showed no clear difference in quality of life at 6 months Assessed by 12‐Item Short Form Health… (low certainty).

• Environmental and behavioural interventions for reducing physical activity limitation and preventing falls in older… 2020 · Cochrane Headline outcomes only
  MD 3.14
  1 study · 28 participants
  Low

Summary of findings: Picture Exchange Communication System (PECS) vs treatment

The review found no eligible studies for this question.

• Communication interventions for autism spectrum disorder in minimally verbal children 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: focused playtime intervention vs treatment

The review found no eligible studies for this question.

• Communication interventions for autism spectrum disorder in minimally verbal children 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found