Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

701 questions · 713 findings · 246 reviews

No studies found 398 · 55.8%GRADE not reported 59 · 8.3%Very low 114 · 16%Low 98 · 13.7%Moderate 40 · 5.6%High 4 · 0.6%

Intervention not reported

General health‐related quality of life: SF‐36 physical component score (range 0 to 100; higher score = better health state) at 2 years · Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)
1 finding from 1 review

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs conservative interventions

Health‐related quality of life (physical) · adults with acute acromioclavicular dislocation of the shouldera
1 finding from 1 review

Pyridoxine vs placebo

Severity, reduction or cessation in nausea/vomiting 2. Quality of life outcomes 3. Pregnancy complications 4. Adverse fetal/neonatal outcomes · Pregnant women with hyperemesis gravidarum

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

HRQoL using EQ‐ 5D (range 0 to 1), SF‐36 (range 0 to 100), SF‐12 (range 0 to 100), and WHOQOL‐BREF (range 0 to 130). A higher score indicates better quality of life. · adults following hip fracture surgery

The intervention showed no clear difference in HRQoL using EQ‐ 5D (range 0 to 1), SF‐36 (range 0 to 100), SF‐12… (moderate certainty).

1 finding from 1 review

Ondansetron vs promethazine

Severity, reduction or cessation in nausea/vomiting 2. Number of episodes of emesis 3. Quality of life outcomes 4. Pregnancy complications 5. Adverse fetal/neonatal outcomes · Pregnant women with hyperemesis gravidarum

The review found no eligible studies for this question.

1 finding from 1 review

Home fall‐hazard reduction vs control (e.g. usual activities)

QoL · older people living in the community (included trials conducting pre‐ and/or post‐hospital discharge home visits focusing on fall…

Home fall‐hazard reduction showed no clear difference in health‐related quality of life SMD was calculated from 4 studies… compared with control (e.g. usual care) (moderate certainty).

1 finding from 1 review

Intravenous soya oil‐derived (n‐6) fatty acid‐based lipid emulsion vs intravenous fish oil‐derived (n‐3) fatty acid‐based lipid emulsion

Improvement in participant satisfaction measures and quality of life assessment measures Overall subjective score on 5 items (appearance of lesions, impairment of daily life, pruritus, burning, and pain) reported through figures · guttate psoriasis
1 finding from 1 review

Intervention not reported

SF‐36 social function. Domain of SF‐36 considered representative of quality of life: mental health domain largely covered by depression and anxiety above: scale of 0‐100. Higher score indicated improved social function. Mean duration of · people with chronic hip, knee or hip and knee osteoarthritis
1 finding from 1 review

Intervention not reported

Global quality of life FLIC total score (Blanchard 1996), FACT‐G total score (Northouse 2007). Additional studies (reported in comments section): FACT‐B physical functioning subscale (Baucom 2009). EPIC multiple subscales and overall scores (Campb... · individuals with cancer (patients)
1 finding from 1 review

Intervention not reported

Global quality of life FLIC total score (Blanchard 1996), EORTC‐QLQ‐C30 global health status score (Ledderer 2013), FACT‐G total score (Northouse 2007). Additional study (reported in comments section): FACT‐B physical functioning subscale (Baucom ... · individuals with cancer (patients)
1 finding from 1 review