Cochrane · systematic review · CD011541
Non‐antistreptococcal interventions for acute guttate psoriasis or an acute guttate flare of chronic psoriasis
Maruani, A, Samimi, M, Stembridge, N, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
SkinAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
1
No studies
4
Included studies
NR
No studies 4 · 80%Ungraded 0 · 0%Very low 1 · 20%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Intravenous soya oil‐derived (n‐6) fatty acid‐based lipid emulsion compared to intravenous fish oil‐derived (n‐3) fatty acid‐based lipid emulsion for guttate psoriasis
Population: guttate psoriasis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Percentage of participants clear or almost clear, i.e. obtaining PASI 100/90 and/or PGA of 0 or 1 in the short term Intravenous soya oil‐derived (n‐6) fatty acid‐based lipid emulsion vs intravenous fish oil‐derived (n‐3) fatty acid‐based lipid emulsion | no estimate extracted | NR | No studies |
Percentage of participants with adverse effects and severe adverse effects Intravenous soya oil‐derived (n‐6) fatty acid‐based lipid emulsion vs intravenous fish oil‐derived (n‐3) fatty acid‐based lipid emulsion | no estimate extracted | NR | No studies |
Number of relapses of guttate psoriasis or flares within a period of 6 months after the treatment has finished Intravenous soya oil‐derived (n‐6) fatty acid‐based lipid emulsion vs intravenous fish oil‐derived (n‐3) fatty acid‐based lipid emulsion | no estimate extracted | NR | No studies |
Percentage of participants achieving a PASI 75 or PGA of 1 or 2 Intravenous soya oil‐derived (n‐6) fatty acid‐based lipid emulsion vs intravenous fish oil‐derived (n‐3) fatty acid‐based lipid emulsion | no estimate extracted | NR | No studies |
Improvement in participant satisfaction measures and quality of life assessment measures Overall subjective score on 5 items (appearance of lesions, impairment of daily life, pruritus, burning, and pain) reported through figures Intravenous soya oil‐derived (n‐6) fatty acid‐based lipid emulsion vs intravenous fish oil‐derived (n‐3) fatty acid‐based lipid emulsion | no estimate extracted | 1 study · 21 participants | Very low Downgraded: risk of bias, imprecision, indirectness |