Findings

What do systematic reviews say?

169 questions · 172 findings · 72 reviews

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No studies found 69 · 40.1%GRADE not reported 9 · 5.2%Very low 35 · 20.3%Low 40 · 23.3%Moderate 19 · 11%High 0 · 0%

Recombinant human C1 esterase inhibitor vs placebo or active control

Differences in quality of life ( · children or adults with Types I or II HAE

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cannabis oil (15% cannabidiol and 4% THC) vs placebo oil

Quality of life Short‐Form 36 health survey (SF‐36) · Patients with active Crohn's disease

1 finding from 1 review

Cannabis for the treatment of Crohn's disease 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Cannabis cigarettes (115 mg THC) vs placebo cigarettes

Quality of life Short‐Form 36 health survey (SF‐36) · Patients with active Crohn's disease

The review found no eligible studies for this question.

1 finding from 1 review

Cannabis for the treatment of Crohn's disease 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CBT vs active control

Quality of life (Higher scores indicate improvement) · chronic pain (excluding headache) in adults

2 findings from 1 review

Psychological therapies delivered remotely for the management of chronic pain (excluding headache) in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 261 participants
Moderate
Psychological therapies delivered remotely for the management of chronic pain (excluding headache) in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 127 participants
Very low

Bronchial thermoplasty vs active control

Health‐related quality of life (AQLQ)Scale from: 1‐7 (higher is better) · adults with asthma

1 finding from 1 review

Bronchial thermoplasty for moderate or severe persistent asthma in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 429 participants
Moderate

Intervention not reported

Overall quality of life change score ‐ up to 12 weeks' · Cancer survivors who have completed active cancer treatment

1 finding from 1 review

Exercise interventions on health‐related quality of life for cancer survivors 2012 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 826 participants
Low

Summary of findings table ‐ Cognitive rehabilitation vs inactive control

Quality of life: psychological (care partner self‐report) · people with mild‐to‐moderate dementia (at medium‐term follow‐up)

1 finding from 1 review

Cognitive rehabilitation for people with mild to moderate dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 437 participants
Moderate

Summary of findings table ‐ Cognitive rehabilitation vs inactive control

Quality of life: psychological (care partner self‐report) · people with mild‐to‐moderate dementia (at the end of therapy)

1 finding from 1 review

Cognitive rehabilitation for people with mild to moderate dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 464 participants
Moderate

Cognitive training vs active control

Quality of life: clinically important change in quality of life · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Cannabis cigarettes vs placebo

Health‐related quality of life (timeframe not reported) ‐ IBDQ ‐ Symptoms‐guided diet · people with active UC

The review found no eligible studies for this question.

1 finding from 1 review

Cannabis for the treatment of ulcerative colitis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

SPLINT vs No active treatment (control)

Health‐related quality of life ‐ Long‐term improvement: > 3 months · carpal tunnel syndrome

1 finding from 1 review

Splinting for carpal tunnel syndrome 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Lanadelumab vs placebo or active control

Differences in quality of life ( · children or adults with Types I or II HAE

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 68 participants
Low

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Quality of life ‐ after 48 months Number of participants: 1325(1 RCT)

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

C1 esterase inhibitor vs placebo or active control

Improvement in quality of life: the difference in quality of life scores for participants surveyed before and after treatment · children or adults with Types I or II HAE

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
Low

Nanofiltered C1 esterase inhibitor vs placebo or active control

Improvement in quality of life: the difference in quality of life scores for participants surveyed before and after treatment · children or adults with Types I or II HAE

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Fecal microbiota transplantation vs control

Quality‐of‐life scores with use of FMT for induction of remission in CD · Patients with active Crohn's disease

1 finding from 1 review

Fecal transplantation for treatment of inflammatory bowel disease 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention diet vs control diet

Health related quality of life at 12 months ‐ SIBDQ ‐ Carrageenan‐free diet · Patients with quiescent ulcerative colitis

1 finding from 1 review

Dietary interventions for induction and maintenance of remission in inflammatory bowel disease 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Very low

Cannabidiol vs placebo

IBDQ at week 6 · people with active UC

1 finding from 1 review

Cannabis for the treatment of ulcerative colitis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 53 participants
Moderate

Electrical stimulation vs No active treatment (control)

Incontinence‐specific quality of life · women with stress urinary incontinence

1 finding from 1 review

Electrical stimulation with non‐implanted devices for stress urinary incontinence in women 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 250 participants
Moderate

Berotralstat vs placebo or active control

Quality of lifeAngioedema Quality of Life scale (lower score is better)(during · children or adults with Types I or II HAE

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 130 participants
Moderate