Cochrane · systematic review · CD009910

Bronchial thermoplasty for moderate or severe persistent asthma in adults

Torrego, A, Solà, I, Munoz, AM, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 16.7%Very low 0 · 0%Low 1 · 16.7%Moderate 3 · 50%High 1 · 16.7%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Bronchial thermoplasty compared with any active control for persistent asthma in adults

Population: adult patients with asthma
6 questions
OutcomeEffectEvidenceStatus / GRADE
Quality of life (AQLQ) AQLQ scores1. Scale from 1 to 7
Bronchial thermoplasty vs any active control
no estimate extracted3 studies · 429 participantsModerate
Asthma control (ACQ) ACQ scores. Scale from 0 to 36
Bronchial thermoplasty vs any active control
no estimate extracted3 studies · 429 participantsModerate
Number of exacerbations
Bronchial thermoplasty vs any active control
no estimate extracted2 studies · 409 participantsUngraded
Participants admitted to hospital because of respiratory adverse events (treatment period)
Bronchial thermoplasty vs any active control
RR 3.5 [1.26, 9.68]3 studies · 429 participantsHigh
Participants admitted to hospital because of respiratory adverse events (post‐treatment period)
Bronchial thermoplasty vs any active control
RR 1.12 [0.44, 2.85]3 studies · 429 participantsModerate
Downgraded: imprecision
Use of rescue medication Short‐acting bronchodilator puffs per week
Bronchial thermoplasty vs any active control
no estimate extracted3 studies · 429 participantsLow
Downgraded: imprecision