Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

95 questions · 97 findings · 43 reviews

No studies found 1 · 1%GRADE not reported 30 · 30.9%Very low 15 · 15.5%Low 25 · 25.8%Moderate 15 · 15.5%High 11 · 11.3%

Periodontitis (exposure) vs No periodontitis

Preterm birth (<37 weeks) · Pregnant women

Periodontitis definition: >=4 teeth with PPD >=4 mm and CAL >=3 mm at the same site: OR 2.86 (1.79 to 4.56) for preterm birth, significant.

1 finding from 1 review

Periodontitis (exposure) vs No periodontitis

Preterm birth (<37 weeks) · Pregnant women

Studies including participants with history of urinary tract infection: OR 2.38 (1.63 to 3.49) for preterm birth, significant.

1 finding from 1 review

Intervention not reported

Any preterm birth (birth < 37 weeks) · women with a previous stillbirth of > 20 weeks' gestation who are pregnant or considering a subsequent pregnancy

It is very uncertain whether the intervention changes any preterm birth (birth < 37 weeks) (very low certainty).

1 finding from 1 review

Intervention not reported

Any preterm birth (birth < 37 weeks) · women with a previous stillbirth of ≥ 20 weeks' gestation who are pregnant or considering a subsequent pregnancy

The intervention showed no clear difference in any preterm birth (birth < 37 weeks) (low certainty).

1 finding from 1 review

Intramuscular (IM) progesterone vs no treatment or placebo

Preterm birth less than 34 weeks' gestation · Women with a multiple pregnancy

Intramuscular (IM) progesterone may leads to higher preterm birth less than 34 weeks compared with no treatment or placebo (low certainty).

1 finding from 1 review