Question · asked by 1 review

SOF Immunological sealant vs usual care: Preterm birth

Population
preterm prelabour rupture of membranes (PPROM)
Intervention
SOF Immunological sealant
Comparison
usual care
Outcome
Preterm birth

It is very uncertain whether SOF Immunological sealant changes preterm birth less than 37 weeks' gestation compared with standard care (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
SOF Immunological sealant vs standard care
Preterm birth less than 37 weeks' gestation · preterm prelabour rupture of membranes (PPROM)
It is very uncertain whether SOF Immunological sealant changes preterm birth less than 37 weeks' gestation compared with standard care (very low certainty).
Sealing procedures for preterm prelabour rupture of membranes (2016) · Cochrane Headline outcomes only
RR 0.48 [0.34, 0.68]1 study · 94 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Sealing procedures for preterm prelabour rupture of membranes
2016 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.