Question · asked by 1 review
Vaginal progesterone vs no treatment or placebo: Preterm birth less than 28 weeks
- Population
- Women with a multiple pregnancy
- Intervention
- Vaginal progesterone
- Comparison
- no treatment or placebo
- Outcome
- Preterm birth less than 28 weeks
Vaginal progesterone showed no clear difference in preterm birth less than 28 weeks compared with no treatment or placebo (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Vaginal progesterone vs no treatment or placebo Preterm birth less than 28 weeks · Women with a multiple pregnancy Vaginal progesterone showed no clear difference in preterm birth less than 28 weeks compared with no treatment or placebo (low certainty). Prenatal administration of progestogens for preventing spontaneous preterm birth in women with a multiple… (2019) · Cochrane Headline outcomes only | RR 1.53 [0.79, 2.97] | 3 studies · 1345 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Prenatal administration of progestogens for preventing spontaneous preterm birth in women with a multiple pregnancy 2019 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.