Mortality (all cause) · addition to tiotropium versus either tiotropium or LABA alone for chronic obstructive pulmonary disease
Long‐acting beta2‐agonist plus tiotropium showed no clear difference in mortality (all cause) compared with long‐acting beta2‐agonist alone (low certainty).
1 finding from 1 review
Mortality (all‐cause) · patients with chronic obstructive pulmonary disease
Long‐acting beta2‐agonists showed no clear difference in mortality (all‐cause) compared with placebo (moderate certainty).
1 finding from 1 review
Mortality (all cause) · addition to tiotropium versus either tiotropium or LABA alone for chronic obstructive pulmonary disease
Long‐acting beta2‐agonist plus tiotropium showed no clear difference in mortality (all cause) compared with tiotropium alone (low certainty).
1 finding from 1 review
Intervention not reported
Long‐term mortality (> 36 months) · patients with diffuse emphysema
The intervention probably leads to lower long‐term mortality (> 36 months) (moderate certainty).
1 finding from 1 review
Intervention not reported
Mortality · adults with COPD who had exertional dyspnoea but did not fulfil the criteria for long‐term oxygen treatment
The intervention showed no clear difference in mortality (moderate certainty).
1 finding from 1 review
Long‐term survival (incidence of mortality) · idiopathic pulmonary fibrosis
Pulmonary rehabilitation showed no clear difference in long‐term survival (incidence of mortality) compared with no pulmonary rehabilitation (low certainty).
1 finding from 1 review
Long‐term survival (incidence of mortality) · interstitial lung disease
Pulmonary rehabilitation showed no clear difference in long‐term survival (incidence of mortality) compared with no pulmonary rehabilitation (low certainty).
1 finding from 1 review
All‐cause mortality · COPD and at least one other long‐term condition
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mortality (all‐cause) · patients with stable chronic obstructive pulmonary disease and > 10 pack years smoking history
It is very uncertain whether tiotropium changes mortality (all‐cause) compared with long‐acting beta‐agonists (very low certainty).
1 finding from 1 review
All‐cause mortality (deaths) Â · COPD and at least one other long‐term condition
It is very uncertain whether intervention changes all‐cause mortality (deaths) Â compared with usual care (very low certainty).
1 finding from 1 review
Intervention not reported
Mortality · patients with COPD
The intervention leads to lower mortality (high certainty).
1 finding from 1 review
All‐cause mortality · COPD
Combined inhalers showed no clear difference in mortality compared with LABAs (moderate certainty).
1 finding from 1 review
Mortality Deaths · patients with chronic obstructive pulmonary disease
Indacaterol showed no clear difference in mortality Deaths compared with twice‐daily long‐acting beta2‐agonists (moderate certainty).
1 finding from 1 review
Mortality (all‐cause) · stable COPD
Triple therapy may leads to lower mortality (all‐cause) compared with LABA/LAMA combination (low certainty).
1 finding from 1 review
Mortality (all‐cause) · patients with chronic obstructive pulmonary disease
It is very uncertain whether once‐daily ICS/LABA combined inhalers changes mortality (all‐cause) compared with once‐daily LAMA (very low certainty).
1 finding from 1 review
Mortality (all‐cause) · patients with chronic obstructive pulmonary disease
Tiotropium + LABA/ICS combination showed no clear difference in mortality (all‐cause) compared with tiotropium (moderate certainty).
1 finding from 1 review
Mortality Duration of 18 months3 · COPD
Combined inhalers probably leads to lower mortality Duration of 18 months3 compared with placebo (primary outcomes) (moderate certainty).
1 finding from 1 review
All‐cause mortality (3‐week to 1‐year · Adults with COPD
Once‐daily LABA/LAMA in a combined inhaler showed no clear difference in all‐cause mortality (3‐week to 1‐year compared with placebo (low certainty).
1 finding from 1 review