Findings

What do systematic reviews say?

14 questions · 14 findings · 12 reviews · Emergency and Critical Care

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 28.6%Low 4 · 28.6%Moderate 4 · 28.6%High 2 · 14.3%

HALOPERIDOL vs placebo

Duration of ICU stay · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…

1 finding from 1 review

Interventions for preventing intensive care unit delirium in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1580 participants
High

Protocol‐directed sedation management vs usual care

Duration of ICU stay · mechanically ventilated ICU adults and children requiring sedation management

1 finding from 1 review

Protocol‐directed sedation versus non‐protocol‐directed sedation in mechanically ventilated intensive care adults and… 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 3128 participants
Low

Physical and cognitive therapy vs usual care

Duration of ICU stay · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…

It is very uncertain whether physical and cognitive therapy changes length of ICU stay (days) compared with standard care (very low certainty).

1 finding from 1 review

Interventions for preventing intensive care unit delirium in adults 2018 · Cochrane Headline outcomes only
MD 1.23
1 study · 65 participants
Very low

Etomidate vs all other induction agents

Duration of ICU stay · patients with endotracheal intubation in critically ill patients

1 finding from 1 review

Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 621 participants
Moderate

Intervention not reported

ICU length of stay (days) · mechanically ventilated adult patients

1 finding from 1 review

Protocolized versus non‐protocolized weaning for reducing the duration of mechanical ventilation in critically ill… 2014 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1378 participants
Low

Daily sedation interruption vs usual care or protocolized sedation strategies that do not include daily sedation interruption

Duration of ICU stay · Critically ill adults receiving mechanical ventilation in ICU

Daily sedation interruption showed no clear difference in ICU length of stay (days) compared with usual care or protocolized sedation strategies that do not include… (moderate certainty).

1 finding from 1 review

Daily sedation interruption versus no daily sedation interruption for critically ill adult patients requiring invasive… 2014 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1282 participants
Moderate

Intervention not reported

ICU length of stay (days) · critically ill adults and children requiring weaning from mechanical ventilation

The intervention showed no clear difference in ICU length of stay (days) (moderate certainty).

1 finding from 1 review

Automated versus non‐automated weaning for reducing the duration of mechanical ventilation for critically ill adults… 2014 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 1339 participants
Moderate

Automated monitoring systems vs usual care

Duration of ICU stay · people admitted to intensive care units

1 finding from 1 review

Automated monitoring compared to standard care for the early detection of sepsis in critically ill patients 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 442 participants
Very low

Pressure support vs T‐tube

ICU or LWU length of stay (days) · patients on weaning from mechanical ventilation in adults.

1 finding from 1 review

Pressure support versus T‐tube for weaning from mechanical ventilation in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 118 participants
Low

Hypocaloric nutrition vs control

ICU length of stay (general intensive care patients) · critically ill adult patients

1 finding from 1 review

Prescribed hypocaloric nutrition support for critically‐ill adults 2018 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 2942 participants
Very low

Intervention not reported

Length of stay on the intensive care unit (days) · Adult patients with SIRS or sepsis

1 finding from 1 review

N‐acetylcysteine for sepsis and systemic inflammatory response in adults 2012 · Cochrane Headline outcomes only
no estimate extracted
19 studies · 1309 participants
Moderate

Corticosteroids vs placebo or usual care

ICU length of stay (general intensive care patients) · children and adults with sepsis

1 finding from 1 review

Corticosteroids for treating sepsis in children and adults 2019 · Cochrane Headline outcomes only
no estimate extracted
21 studies · 7612 participants
High

Bispectral index vs treatment guided by clinical assessment alone?

ICU length of stay (general intensive care patients) · Mechanically ventilated adults in the intensive care unit

1 finding from 1 review

BIS monitoring versus clinical assessment for sedation in mechanically ventilated adults in the intensive care unit… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Hypocaloric nutrition vs control

Duration of mechanical ventilation · critically ill adult patients

1 finding from 1 review

Prescribed hypocaloric nutrition support for critically‐ill adults 2018 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 3000 participants
Very low