Cochrane · systematic review · CD011240
BIS monitoring versus clinical assessment for sedation in mechanically ventilated adults in the intensive care unit and its impact on clinical outcomes and resource utilization
Shetty, RM, Bellini, A, Wijayatilake, DS, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
Emergency and Critical CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
3
No studies
1
Included studies
NR
No studies 1 · 25%Ungraded 0 · 0%Very low 1 · 25%Low 2 · 50%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
BIS monitoring compared to clinical assessment for sedation in mechanically ventilated adults in the intensive care unit and its impact on clinical outcomes and resource utilization
Population: Mechanically ventilated adults in the intensive care unit
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intensive care unit length of stay (ICU LOS) (measured in days) BIS monitoring vs clinical assessment | no estimate extracted | 1 study · 50 participants | Low Downgraded: imprecision |
Duration of mechanical ventilation (measured in days) BIS monitoring vs clinical assessment | no estimate extracted | 2 studies · 155 participants | Low Downgraded: risk of bias, imprecision, indirectness |
Adverse events: Measured as number of patients with adverse events BIS monitoring vs clinical assessment | no estimate extracted | 1 study · 105 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Other important secondary outcomes like Any‐cause mortality, ventilator‐associated pneumonia, hospital LOS, amount of sedative agents used, long term functional outcomes and quality of life were not reported in any studies BIS monitoring vs clinical assessment | no estimate extracted | NR | No studies |