Cochrane · systematic review · CD012404

Automated monitoring compared to standard care for the early detection of sepsis in critically ill patients

Warttig, S, Alderson, P, Evans, DJW, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Emergency and Critical CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
4
No studies
2
Included studies
NR
No studies 2 · 33.3%Ungraded 0 · 0%Very low 4 · 66.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Automated monitoring systems compared to standard care for detecting sepsis

Population: participants of any age admitted to the intensive care or critical care unit for any reason (including, but not limited to postsurgery, trauma, stroke, myocardial infarction, arrhythmia, burns, and hypovolaemic or haemorrhagic shock)
6 questions
OutcomeEffectEvidenceStatus / GRADE
Time to initiation of antimicrobial therapy (Time to initiation starts at the time of admission)
Automated monitoring systems vs standard care
no estimate extracted3 studies · 1200 participantsVery low
Downgraded: risk of bias
Time to initiation of fluid resuscitation (Time to initiation starts at the time of admission)
Automated monitoring systems vs standard care
no estimate extractedNRNo studies
30‐day mortality*
Automated monitoring systems vs standard care
no estimate extractedNRVery low
Downgraded: risk of bias
Length of stay in ICU (in days)
Automated monitoring systems vs standard care
no estimate extracted1 study · 442 participantsVery low
Downgraded: risk of bias
Failed detection of sepsis (as reported by studies)
Automated monitoring systems vs standard care
no estimate extracted1 study · 560 participantsVery low
Downgraded: risk of bias
Quality of life measured at the latest available time point post‐discharge from ICU (preferred measure SF‐36 then EQ‐5D)
Automated monitoring systems vs standard care
no estimate extractedNRNo studies