Findings

What do systematic reviews say?

56 questions · 59 findings · 28 reviews

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No studies found 12 · 20.3%GRADE not reported 1 · 1.7%Very low 21 · 35.6%Low 14 · 23.7%Moderate 11 · 18.6%High 0 · 0%

Multimodal intervention (exercise plus other interventions) plus usual care vs usual care

Fatigue · cancer cachexia in adults

1 finding from 1 review

Exercise for cancer cachexia in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
Very low

Exercise therapy vs control

FatigueMeasured after 52‐70 weeks · men and women aged over 18 years with chronic fatigue syndrome

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 670 participants
Very low

Exercise therapy vs antidepressants

FatigueMeasured at end of treatment, 26 weeks · men and women aged over 18 years with chronic fatigue syndrome

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Very low

Exercise therapy vs adaptive pacing therapy

Fatigue · men and women aged over 18 years with chronic fatigue syndrome

2 findings from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 305 participants
Low
Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 307 participants
Low

Exercise therapy vs control

FatigueMeasured at end of treatment, 26 weeks · men and women aged over 18 years with chronic fatigue syndrome

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 840 participants
Moderate

Aerobic exercise vs no training

Fatigue · people with facioscapulohumeral muscular dystrophy

1 finding from 1 review

Strength training and aerobic exercise training for muscle disease 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Ai Chi Exercises vs sham

Reduction in fatigue · chronic musculoskeletal pain in people with MS

1 finding from 1 review

Non‐pharmacological interventions for chronic pain in multiple sclerosis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 73 participants
Very low

MX exercise training vs control

Fatigue · patients with fibromyalgia

1 finding from 1 review

Mixed exercise training for adults with fibromyalgia 2019 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 493 participants
Moderate

Exercise therapy plus antidepressants vs antidepressants alone

Fatigue · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Aerobic exercise and strength training vs no training

Fatigue · people with mitochondrial myopathy

The review found no eligible studies for this question.

1 finding from 1 review

Strength training and aerobic exercise training for muscle disease 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Aerobic exercise and strength training vs no training

Fatigue · people with myotonic dystrophy type 1

The review found no eligible studies for this question.

1 finding from 1 review

Strength training and aerobic exercise training for muscle disease 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Aerobic exercise and strength training vs no training

Fatigue · people with dermatomyositis and polymyositis

The review found no eligible studies for this question.

1 finding from 1 review

Strength training and aerobic exercise training for muscle disease 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Aerobic exercise and strength training vs no training

Fatigue · people with facioscapulohumeral muscular dystrophy

1 finding from 1 review

Strength training and aerobic exercise training for muscle disease 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Aerobic exercise and strength training vs no training

Fatigue · children and adolescents with juvenile dermatomyositis

1 finding from 1 review

Strength training and aerobic exercise training for muscle disease 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Aerobic exercise vs control

Fatigue · patients with fibromyalgia

1 finding from 1 review

Aerobic exercise training for adults with fibromyalgia 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 246 participants
Low

Cardiorespiratory exercise programmes prescribed alone vs a non‐exercise intervention or no intervention

Fatigue · Treating patients with traumatic brain injury

1 finding from 1 review

Fitness training for cardiorespiratory conditioning after traumatic brain injury 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 130 participants
Very low

Aerobic exercise and strength training vs usual care

Fatigue In children, · children and adults with SMA type 3

1 finding from 1 review

Physical exercise training for type 3 spinal muscular atrophy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Very low

Exercise therapy plus antidepressants vs antidepressants alone

FatigueMeasured at end of treatment, 26 weeks · men and women aged over 18 years with chronic fatigue syndrome

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Very low

Whole body vibration plus mixed exercise vs control

Fatigue · patients with fibromyalgia

1 finding from 1 review

Whole body vibration exercise training for fibromyalgia 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Very low

Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo + standard care

Fatigue · systemic lupus erythematosus

1 finding from 1 review

Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Low