Cochrane · systematic review · CD013340

Mixed exercise training for adults with fibromyalgia

Bidonde, J, Busch, AJ, Schachter, CL, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

MusculoskeletalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 1 · 14.3%Moderate 5 · 71.4%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

MX exercise training compared to control for fibromyalgia

Population: individuals with fibromyalgia
7 questions
OutcomeEffectEvidenceStatus / GRADE
HRQL FIQ Total. Scale from 0 to 100; high scores indicate worse quality of life Median length of interventions: 12 weeks
MX exercise training vs control
no estimate extracted13 studies · 610 participantsModerate
Downgraded: risk of bias, inconsistency
Pain FIQ Pain, VAS, and SF‐36 Bodily Pain. Scale from 0 to 100; high scores indicate worse pain Median length of interventions: 12 weeks
MX exercise training vs control
no estimate extracted15 studies · 832 participantsModerate
Downgraded: risk of bias
Fatigue FIQ Fatigue, VAS, and SF‐36 vitality. Scale from 0 to 100; high scores indicate worse fatigue Median length of interventions: 16 weeks
MX exercise training vs control
no estimate extracted11 studies · 493 participantsModerate
Downgraded: risk of bias
Stiffness FIQ Stiffness and VAS. Scale from: 0 to 100; high scores indicate worse stiffness Median length of interventions: 12 weeks
MX exercise training vs control
no estimate extracted5 studies · 261 participantsLow
Downgraded: risk of bias
Physical function FIQ Physical Function, SF‐36 Physical Function, AIMS, and HAQ. Scale converted to 0 to 100; high scores indicate worse physical function Median length of interventions: 12 weeks
MX exercise training vs control
no estimate extracted9 studies · 477 participantsModerate
Downgraded: risk of bias
All‐cause withdrawal All‐cause withdrawals from studies Median length of interventions: 16 weeks
MX exercise training vs control
RR 1.02 [0.69, 1.51]19 studies · 1065 participantsModerate
Downgraded: risk of bias
Adverse events ‐ increase in symptoms, injuries, or serious adverse events
MX exercise training vs control
no estimate extractedNRVery low
Downgraded: risk of bias