Cochrane · systematic review · CD003907
Strength training and aerobic exercise training for muscle disease
Voet, NBM, van der Kooi, EL, van Engelen, BGM, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
72
current version
GRADE rated
46
No studies
26
Included studies
NR
No studies 26 · 36.1%Ungraded 0 · 0%Very low 29 · 40.3%Low 17 · 23.6%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsStrength training compared to no training for myotonic dystrophy
Population: people with myotonic dystrophy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Muscle strength Strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision, inconsistency |
Aerobic capacity Strength training vs no training | no estimate extracted | NR | No studies |
Time‐scored functional assessments of muscle performance Strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision, inconsistency |
Quality of life Strength training vs no training | no estimate extracted | NR | No studies |
Pain Strength training vs no training | no estimate extracted | NR | No studies |
Experienced fatigue Strength training vs no training | no estimate extracted | NR | No studies |
Adverse effects requiring withdrawal Strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Strength training compared to no training for facioscapulohumeral muscular dystrophy
Population: people with facioscapulohumeral muscular dystrophy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Muscle strength: maximum voluntary isometric contraction Strength training vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Aerobic capacity Strength training vs no training | no estimate extracted | NR | No studies |
Time‐scored functional assessments of muscle performance Strength training vs no training | no estimate extracted | NR | No studies |
Quality of life Strength training vs no training | no estimate extracted | NR | No studies |
Pain Strength training vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Experienced fatigue Strength training vs no training | no estimate extracted | NR | No studies |
Adverse effects requiring withdrawal Strength training vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Aerobic exercise compared to no training for dermatomyositis and polymyositis
Population: people with dermatomyositis and polymyositis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Muscle strength Aerobic exercise vs no training | no estimate extracted | NR | No studies |
Aerobic capacity: VO2 max (defined as the highest O2 consumption) Aerobic exercise vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision, indirectness |
Time‐scored functional assessments of muscle performance: disability Aerobic exercise vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision, indirectness |
Quality of life Aerobic exercise vs no training | no estimate extracted | NR | No studies |
Pain Aerobic exercise vs no training | no estimate extracted | NR | No studies |
Experienced fatigue Aerobic exercise vs no training | no estimate extracted | NR | No studies |
Adverse effects requiring withdrawal Aerobic exercise vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision, indirectness |
Aerobic exercise compared to no training for Duchenne muscular dystrophy (DMD)
Population: boys with DMD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Muscle strength: hip extensors, knee extensors, ankle dorsiflexors, shoulder abductors and elbow extensors Aerobic exercise vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Aerobic capacity Aerobic exercise vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Time‐scored functional assessments of muscle performance: functional abilities in 3 different dimensions, standing positions and transfers, axial and proximal motor functions and distal motor function Aerobic exercise vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Quality of life Aerobic exercise vs no training | no estimate extracted | NR | No studies |
Pain Aerobic exercise vs no training | no estimate extracted | NR | No studies |
Experienced fatigue Aerobic exercise vs no training | no estimate extracted | NR | No studies |
Adverse effects requiring withdrawal Aerobic exercise vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Aerobic exercise compared to no training for facioscapulohumeral muscular dystrophy
Population: people with facioscapulohumeral muscular dystrophy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Muscle strength: maximum voluntary isometric knee extension strength Aerobic exercise vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Aerobic capacity: VO2 peak Aerobic exercise vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Time‐scored functional assessments of muscle performance: distance walked Aerobic exercise vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Quality of life Aerobic exercise vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Pain Asssesed with a Visual Analogue Scale Scale from 0 to 100 Aerobic exercise vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Experienced fatigue Assesed with Checklist Individual Strength Scale from 7 to 56 Aerobic exercise vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Adverse effects requiring withdrawal Aerobic exercise vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Aerobic exercise and strength training compared to no training for mitochondrial myopathy
Population: people with mitochondrial myopathy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Muscle strength: the heaviest weight that could be lifted throughout the complete range of movement (1RM test) Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Aerobic capacity: measures of (physical) work capacity Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Aerobic capacity: distance walked until exhaustion Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Time‐scored functional assessments of muscle performance Aerobic exercise and strength training vs no training | no estimate extracted | NR | No studies |
Quality of life Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Pain Aerobic exercise and strength training vs no training | no estimate extracted | NR | No studies |
Experienced fatigue Aerobic exercise and strength training vs no training | no estimate extracted | NR | No studies |
Adverse effects requiring withdrawal Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Aerobic exercise and strength training compared to no training for myotonic dystrophy type 1
Population: people with myotonic dystrophy type 1
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Muscle strength Aerobic exercise and strength training vs no training | no estimate extracted | NR | No studies |
Aerobic capacity Aerobic exercise and strength training vs no training | no estimate extracted | NR | No studies |
Time‐scored functional assessments of muscle performance: distance walked Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Quality of life Aerobic exercise and strength training vs no training | no estimate extracted | NR | No studies |
Pain Aerobic exercise and strength training vs no training | no estimate extracted | NR | No studies |
Experienced fatigue Aerobic exercise and strength training vs no training | no estimate extracted | NR | No studies |
Adverse effects requiring withdrawal Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Aerobic exercise and strength training compared to no training for dermatomyositis and polymyositis
Population: people with dermatomyositis and polymyositis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Muscle strength 21 participants (1 RCT) Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Aerobic capacity, expressed in measures of (physical) work capacity Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Aerobic capacity: VO2 max Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: imprecision |
Time‐scored functional assessments of muscle performance: muscle performance Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: imprecision |
Quality of life Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Pain Aerobic exercise and strength training vs no training | no estimate extracted | NR | No studies |
Experienced fatigue Aerobic exercise and strength training vs no training | no estimate extracted | NR | No studies |
Adverse effects requiring withdrawal Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Aerobic exercise and strength training compared to no training for facioscapulohumeral muscular dystrophy
Population: people with facioscapulohumeral muscular dystrophy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Muscle strength: MVC quadriceps at rest Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Aerobic capacity Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Time‐scored functional assessments of muscle performance: distance walked Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Quality of life Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Pain Aerobic exercise and strength training vs no training | no estimate extracted | NR | No studies |
Experienced fatigue Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Adverse effects requiring withdrawal Aerobic exercise and strength training vs no training | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Aerobic exercise and strength training compared to no training for juvenile dermatomyositis
Population: children and adolescents with juvenile dermatomyositis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Muscle strength Aerobic exercise and strength training vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Aerobic capacity Aerobic exercise and strength training vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Time‐scored functional assessments of muscle performance: distance walked in meters Aerobic exercise and strength training vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Quality of life Aerobic exercise and strength training vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Pain Aerobic exercise and strength training vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Experienced fatigue Aerobic exercise and strength training vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Adverse effects requiring withdrawal Aerobic exercise and strength training vs no training | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |