Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

247 questions · 259 findings · 100 reviews

No studies found 51 · 19.7%GRADE not reported 26 · 10%Very low 92 · 35.5%Low 59 · 22.8%Moderate 29 · 11.2%High 2 · 0.8%

Psychological interventions vs treatment

Incidence of depression ‐ post‐intervention: 0 months · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether psychological interventions changes incidence of depression ‐ post‐intervention: 0 months compared with treatment (very low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Depression symptoms ‐ intermediate term (1 to 6 months post intervention) GHQ‐12a; PHQ‐9d,e,f; self‐reporting questionnaireh (higher score = higher severity) · adults with post‐traumatic stress and CMDs
1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Depression symptoms ‐ intermediate term (1 to 6 months post intervention) GHQ‐12a; PHQ‐9d,e,f; self‐reporting questionnaireh (higher score = higher severity) · women with perinatal depression
1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Severity of CMD symptoms (including anxiety and depression) ‐ intermediate term (1 to 6 months post intervention) Measured by PHQ‐9a,d,f; SRQ‐20b (higher score, higher severity) · adults with common mental disorders
1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Depression recovery ‐ intermediate term (1 to 6 months post intervention) · women with perinatal depression

Lay health worker‐led psychosocial interventions may leads to higher recovery from depression ‐ intermediate term (1 to 6 months post… compared with enhanced usual care (low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Incidence of depression ‐ post‐intervention: 0 months · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes incidence of depression ‐ post‐intervention: 0 months compared with placebo (very low certainty).

1 finding from 1 review

Primary health professional‐led psychological interventions vs usual care or no treatment

Depression symptoms (1 to 6 months post intervention) Hopkins Symptom Checklist ‐ depression (higher score = higher severity) · adults with post‐traumatic stress or common mental disorders

It is very uncertain whether primary health professional‐led psychological interventions changes depression symptoms (1 to 6 months post intervention) Hopkins… compared with usual or no care (very low certainty).

1 finding from 1 review

Primary health professional‐led psychological interventions vs usual care or no treatment

Anxiety and depression · adults with post‐traumatic stress or common mental disorders

Primary health professional‐led psychological interventions may leads to higher prevalence of adults with probable depression or anxiety (1 to 6… compared with usual or no care (low certainty).

1 finding from 1 review

Primary health professional‐led or collaborative care vs usual or enhanced care

Depressive symptoms · women with perinatal depression

It is very uncertain whether primary health professional‐led collaborative care interventions changes depression symptoms ‐ intermediate term (1 to 6 months post… compared with usual or enhanced care (very low certainty).

1 finding from 1 review