Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

15 questions · 17 findings · 10 reviews · Headline outcomes only

No studies found 2 · 11.8%GRADE not reported 0 · 0%Very low 9 · 52.9%Low 5 · 29.4%Moderate 1 · 5.9%High 0 · 0%

Non‐surgical vs surgical treatment of oesophageal cancer (primary outcomes)

Long‐term mortality (binary outcome) All‐cause mortality for the duration of · patients with oesophageal cancer

Non‐surgical showed no clear difference in long‐term mortality (binary outcome) All‐cause mortality for the… compared with surgical treatment of oesophageal cancer (primary outcomes) (low certainty).

2 findings from 1 review

Non‐surgical vs surgical treatment of oesophageal cancer (primary outcomes)

Short‐term mortality All‐cause mortality either in‐hospital or within 3 months · patients with oesophageal cancer

It is very uncertain whether non‐surgical changes short‐term mortality All‐cause mortality either in‐hospital or… compared with surgical treatment of oesophageal cancer (primary outcomes) (very low certainty).

1 finding from 1 review

Non‐surgical vs surgical treatment of oesophageal cancer (primary outcomes)

Long‐term mortality (time‐to‐event outcome): radiotherapy versus surgery All‐cause mortality for the duration of · patients with oesophageal cancer

It is very uncertain whether non‐surgical changes long‐term mortality (time‐to‐event outcome): radiotherapy versus… compared with surgical treatment of oesophageal cancer (primary outcomes) (very low certainty).

1 finding from 1 review

Non‐surgical vs surgical treatment of oesophageal cancer (primary outcomes)

Long‐term mortality (time‐to‐event outcome): chemoradiotherapy versus surgery All‐cause mortality for the duration of · patients with oesophageal cancer

Non‐surgical showed no clear difference in long‐term mortality (time‐to‐event outcome): chemoradiotherapy… compared with surgical treatment of oesophageal cancer (primary outcomes) (low certainty).

2 findings from 1 review

Surgical portosystemic shunts vs devascularisation with splenectomy

All‐cause mortality · people with hepatosplenic schistosomiasis

It is very uncertain whether surgical portosystemic shunts changes all‐cause mortality compared with devascularisation with splenectomy (very low certainty).

1 finding from 1 review

Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)

All‐cause mortality at 30 days · people with cirrhotic portal hypertension

It is very uncertain whether surgical portosystemic shunts changes all‐cause mortality at 30 days compared with transjugular intrahepatic portosystemic shunt (TIPS) (very low certainty).

1 finding from 1 review

Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)

All‐cause mortality at 5 years · people with cirrhotic portal hypertension

It is very uncertain whether surgical portosystemic shunts changes all‐cause mortality at 5 years compared with transjugular intrahepatic portosystemic shunt (TIPS) (very low certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

All‐cause mortality · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in all‐cause mortality compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review

Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass

Mortality within the longest · adult surgical patients with the need for cardiopulmonary bypass‐dependent heart surgery

It is very uncertain whether pulmonary artery perfusion with blood changes all‐cause mortality within longest compared with no perfusion during cardiopulmonary bypass (very low certainty).

1 finding from 1 review