Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,228 questions · 1,245 findings · 383 reviews

No studies found 403 · 32.4%GRADE not reported 128 · 10.3%Very low 385 · 30.9%Low 232 · 18.6%Moderate 81 · 6.5%High 16 · 1.3%

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Adverse events: all ‐ other events ‐ not listed above (e.g. dysuria, neck pain, eye discomfort) (secondary outcome) · people with depression after stroke

It is very uncertain whether pharmacological intervention and non‐invasive brain stimulation… changes adverse events: all ‐ other events ‐ not listed above (e.g.… compared with a pharmacological intervention and sham stimulation or usual care… (very low certainty).

1 finding from 1 review

Psychological intervention + orthodontic treatment (palatal crib or palatal arch) vs no treatment

Adverse events · Children with a non-nutritive sucking habit (digit or pacifier)
1 finding from 1 review

Summary of findings table ‐ Selective prevention interventions vs control group

Adverse events at study endpoint · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Indicated prevention interventions vs control group

Adverse events at study endpoint · preventing mental disorders
2 findings from 1 review

Homocysteine‐lowering interventions (Folic Acid, Vitamin B6 and Vitamin B12) vs placebo or usual care

Adverse events · people with or without existing cardiovascular disease, men and women

Homocysteine‐lowering interventions (Vitamin B6 (pyridoxine;… showed no clear difference in adverse events compared with placebo or standard care (high certainty).

1 finding from 1 review

Summary of findings table ‐ Promotion/universal prevention interventions vs control group

Adverse events at study endpoint · preventing mental disorders
2 findings from 1 review

Any of the interventions (CR, SE, SW, sealing with sealant materials, Hall Technique, or NRCC) vs Each other, placebo, or no treatment

Adverse events (any type) and safety of sealant · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

The review found no eligible studies for this question.

1 finding from 1 review