Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

42 questions · 42 findings · 20 reviews · Headline outcomes only

No studies found 14 · 33.3%GRADE not reported 7 · 16.7%Very low 11 · 26.2%Low 5 · 11.9%Moderate 5 · 11.9%High 0 · 0%

Pharmacological interventions vs placebo

acceptability ‐ drop‐outs due to adverse events: post‐intervention · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to adverse events: post‐intervention compared with placebo (very low certainty).

1 finding from 1 review