Cochrane · systematic review · CD012864
Physical activity interventions for disease‐related physical and mental health during and following treatment in people with non‐advanced colorectal cancer
McGettigan, M, Cardwell, CR, Cantwell, MM, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
ColorectalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
7
No studies
2
Included studies
NR
No studies 2 · 22.2%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 44.4%Moderate 3 · 33.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Physical activity compared with usual care in adults with non‐advanced colorectal cancer
Population: adults with non‐advanced colorectal cancer treated surgically or with neoadjuvant or adjuvant therapy, or both
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Physical function Physical activity vs usual care | no estimate extracted | 4 studies · 185 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Disease‐related mental health: depression Physical activity vs usual care | no estimate extracted | 4 studies · 198 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Disease‐related mental health: anxiety Physical activity vs usual care | no estimate extracted | 4 studies · 198 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Overall survival (time interval between enrolment in the study and death of the person from any cause) Physical activity vs usual care | no estimate extracted | NR | No studies |
Recurrence‐free survival (time interval between date of enrolment in the study and the date when colorectal cancer recurs or another cancer occurs during the Physical activity vs usual care | no estimate extracted | NR | No studies |
Adverse events Physical activity vs usual care | no estimate extracted | 8 studies · 305 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Physical fitness: aerobic fitness Physical activity vs usual care | no estimate extracted | 7 studies · 295 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Cancer‐related fatigue Physical activity vs usual care | no estimate extracted | 6 studies · 230 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Health‐related quality of life (HRQoL) Physical activity vs usual care | no estimate extracted | 6 studies · 230 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |