Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

79 questions · 79 findings · 37 reviews

No studies found 17 · 21.5%GRADE not reported 17 · 21.5%Very low 25 · 31.6%Low 12 · 15.2%Moderate 7 · 8.9%High 1 · 1.3%

Oral paracetamol vs placebo

Patients with one or more adverse events · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…

Paracetamol (single oral dose, any dose or formulation; subgroups up… showed no clear difference in patients with one or more adverse events compared with placebo; GRADE not reported.

1 finding from 1 review

Steroid therapy in first episode of nephrotic syndrome: 3 months or more vs 2 months of therapy

Adverse events: hypertension · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in adverse events: hypertension compared with 2 months of therapy (moderate certainty).

1 finding from 1 review

Steroid therapy in first episode of nephrotic syndrome: 3 months or more vs 2 months of therapy

Adverse events: Cushing's syndrome · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in adverse events: Cushing's syndrome compared with 2 months of therapy (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ More time vs less time

Serious adverse events/death: medium‐term outcomes · rehabilitation (medium‐term outcomes)

It is very uncertain whether summary of findings table ‐ More time changes serious adverse events/death: medium‐term outcomes compared with less time (very low certainty).

1 finding from 1 review

Steroid therapy in first episode of nephrotic syndrome: 3 months or more vs 2 months of therapy

Adverse events: psychological disorders · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in adverse events: psychological disorders compared with 2 months of therapy (low certainty).

1 finding from 1 review