Cochrane · systematic review · CD012612

The effect of time spent in rehabilitation on activity limitation and impairment after stroke

Clark, B, Whitall, J, Kwakkel, G, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
17
current version
GRADE rated
14
No studies
3
Included studies
NR
No studies 3 · 17.6%Ungraded 0 · 0%Very low 9 · 52.9%Low 5 · 29.4%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings table ‐ More time compared to less time in rehabilitation (objective one – immediately after intervention)

Population: rehabilitation vs less time spent
6 questions
OutcomeEffectEvidenceStatus / GRADE
Activities of daily living (ADL) outcomes
Summary of findings table ‐ More time vs less time
no estimate extracted19 studies · 864 participantsVery low
Downgraded: risk of bias, publication bias
Activity measures of the upper limb (upper limb activity)
Summary of findings table ‐ More time vs less time
no estimate extracted18 studies · 426 participantsVery low
Downgraded: risk of bias
Activity measures of the lower limb (lower limb activity)
Summary of findings table ‐ More time vs less time
no estimate extracted5 studies · 425 participantsLow
Downgraded: risk of bias
Motor impairment measures of the upper limb (upper limb impairment)
Summary of findings table ‐ More time vs less time
no estimate extracted12 studies · 287 participantsLow
Downgraded: risk of bias, imprecision
Motor impairment measures of the lower limb (lower limb impairment)
Summary of findings table ‐ More time vs less time
no estimate extracted1 study · 51 participantsVery low
Downgraded: risk of bias, imprecision
Serious adverse events/death
Summary of findings table ‐ More time vs less time
RR 1.2 [0.51, 2.85]2 studies · 379 participantsLow
Downgraded: risk of bias

Summary of findings table ‐ More time compared to less time in rehabilitation (objective one – medium‐term outcomes)

Population: rehabilitation (medium‐term outcomes)
6 questions
OutcomeEffectEvidenceStatus / GRADE
Activities of daily living (ADL) outcomes: medium‐term outcomes
Summary of findings table ‐ More time vs less time
no estimate extracted12 studies · 673 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Activity measures of the upper limb: medium‐term outcomes
Summary of findings table ‐ More time vs less time
no estimate extracted9 studies · 218 participantsVery low
Downgraded: risk of bias
Activity measures of the lower limb: medium‐term outcomes
Summary of findings table ‐ More time vs less time
no estimate extracted4 studies · 243 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Motor impairment measures of the upper limb: medium‐term outcomes
Summary of findings table ‐ More time vs less time
no estimate extracted5 studies · 115 participantsVery low
Downgraded: risk of bias
Motor impairment measures of the lower limb: medium‐term outcomes
Summary of findings table ‐ More time vs less time
no estimate extracted1 study · 37 participantsVery low
Downgraded: risk of bias, imprecision
Serious adverse events/death: medium‐term outcomes
Summary of findings table ‐ More time vs less time
RR 1.32 [0.63, 2.76]3 studies · 344 participantsVery low
Downgraded: risk of bias

Summary of findings table ‐ More time compared to less time in rehabilitation (objective one – long‐term outcomes)

Population: rehabilitation (long‐term outcomes)
5 questions
OutcomeEffectEvidenceStatus / GRADE
Activities of daily living (ADL) outcomes: long‐term outcomes
Summary of findings table ‐ More time vs less time
no estimate extracted1 study · 67 participantsLow
Downgraded: imprecision
Activity measures of the lower limb: long‐term outcomes
Summary of findings table ‐ More time vs less time
no estimate extracted1 study · 67 participantsLow
Downgraded: imprecision
Motor impairment measures of the upper limb: long‐term outcomes ‐ not reported
Summary of findings table ‐ More time vs less time
no estimate extractedNRNo studies
Motor impairment measures of the lower limb: long‐term outcomes ‐ not reported
Summary of findings table ‐ More time vs less time
no estimate extractedNRNo studies
Serious adverse events/death: long‐term outcomes ‐ not reported
Summary of findings table ‐ More time vs less time
no estimate extractedNRNo studies