Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

27 questions · 27 findings · 10 reviews · Headline outcomes only

No studies found 7 · 25.9%GRADE not reported 3 · 11.1%Very low 6 · 22.2%Low 8 · 29.6%Moderate 3 · 11.1%High 0 · 0%

Co‐formulated abacavir‐lamivudine‐zidovudine vs NNRTIs or PIs

Severe adverse events · patients with initial treatment of HIV infection in antiretroviral‐naive individuals

Co‐formulated abacavir‐lamivudine‐zidovudine showed no clear difference in severe adverse events compared with NNRTIs or PIs (moderate certainty).

1 finding from 1 review

Oral 5‐aminosalicylic acid vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

Withdrawals due to adverse events · Patients with quiescent ulcerative colitis

It is very uncertain whether oral 5‐aminosalicylic acid changes withdrawal due to adverse events compared with comparator 5‐aminosalicylic acid formulation (very low certainty).

1 finding from 1 review