Cochrane · systematic review · CD013090

Xiao Chai Hu Tang, a herbal medicine, for chronic hepatitis B

Kong, DZ, Liang, N, Yang, GL, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
3
No studies
5
Included studies
NR
No studies 5 · 62.5%Ungraded 0 · 0%Very low 3 · 37.5%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Xiao Chai Hu Tang formula compared with no intervention for chronic hepatitis B

Population: chronic hepatitis B
8 questions
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality
Xiao Chai Hu Tang formula vs no intervention
no estimate extractedNRNo studies
Proportion of participants with ≥ 1 serious adverse events
Xiao Chai Hu Tang formula vs no intervention
no estimate extractedNRNo studies
Health‐related quality of life
Xiao Chai Hu Tang formula vs no intervention
no estimate extractedNRNo studies
Hepatitis B‐related mortality
Xiao Chai Hu Tang formula vs no intervention
no estimate extractedNRNo studies
Hepatitis B‐related morbidity
Xiao Chai Hu Tang formula vs no intervention
no estimate extractedNRNo studies
Proportion of participants with ≥ 1 adverse events considered 'not to be serious' (at maximum
Xiao Chai Hu Tang formula vs no intervention
RR 0.43 [0.02, 11.98]2 studies · 240 participantsVery low
Downgraded: risk of bias, inconsistency
Proportion of participants with detectable HBV‐DNA in serum or plasma (at maximum
Xiao Chai Hu Tang formula vs no intervention
RR 0.62 [0.45, 0.85]3 studies · 222 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Proportion of participants with detectable HBeAg in serum or plasma (at maximum
Xiao Chai Hu Tang formula vs no intervention
RR 0.72 [0.5, 1.02]2 studies · 160 participantsVery low
Downgraded: risk of bias, imprecision, indirectness