Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

28 questions · 28 findings · 11 reviews

No studies found 7 · 25%GRADE not reported 4 · 14.3%Very low 6 · 21.4%Low 8 · 28.6%Moderate 3 · 10.7%High 0 · 0%

Co‐formulated abacavir‐lamivudine‐zidovudine vs NNRTIs or PIs

Severe adverse events · patients with initial treatment of HIV infection in antiretroviral‐naive individuals

Co‐formulated abacavir‐lamivudine‐zidovudine showed no clear difference in severe adverse events compared with NNRTIs or PIs (moderate certainty).

1 finding from 1 review

Oral paracetamol vs placebo

Patients with one or more adverse events · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…

Paracetamol (single oral dose, any dose or formulation; subgroups up… showed no clear difference in patients with one or more adverse events compared with placebo; GRADE not reported.

1 finding from 1 review

Oral 5‐aminosalicylic acid vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

Withdrawals due to adverse events · Patients with quiescent ulcerative colitis

It is very uncertain whether oral 5‐aminosalicylic acid changes withdrawal due to adverse events compared with comparator 5‐aminosalicylic acid formulation (very low certainty).

1 finding from 1 review