Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

211 questions · 212 findings · 75 reviews

No studies found 44 · 20.8%GRADE not reported 17 · 8%Very low 70 · 33%Low 49 · 23.1%Moderate 28 · 13.2%High 4 · 1.9%

Honey vs topical antibiotics

Adverse events: honey versus SSD · people with burns

It is very uncertain whether honey changes adverse events: honey versus SSD compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 0.2 [0.01, 3.97]
    3 studies · 250 participants
    Very low

Macrolides vs placebo

Serious adverse events · children with bronchiectasis

Macrolides showed no clear difference in serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Macrolides vs placebo

Serious adverse events · adults with bronchiectasis

Macrolides showed no clear difference in serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Topical prophylaxis vs no topical prophylaxis

Allergic adverse events · adults receiving mechanical ventilation for at least 48 hours

It is very uncertain whether topical prophylaxis changes allergic adverse events compared with no topical prophylaxis (very low certainty).

1 finding from 1 review

Topical plus systemic prophylaxis vs placebo or no treatment

Allergic adverse events · adults receiving mechanical ventilation for at least 48 hours

Topical plus systemic prophylaxis showed no clear difference in allergic adverse events compared with placebo or no treatment (low certainty).

1 finding from 1 review

Summary of findings: cycled vs culture‐based antibiotic therapy

Adverse events: severe adverse events (total) · children (aged 1 to 12 years) with CF and a newly isolated PA infection

Summary of findings: cycled showed no clear difference in adverse events: severe adverse events (total) compared with culture‐based antibiotic therapy (moderate certainty).

1 finding from 1 review

Intervention not reported

Secondary ‐ Adverse events · Patients with acute uncomplicated diverticulitis

The intervention showed no clear difference in secondary ‐ Adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Secondary ‐ Adverse events · Patients with acute uncomplicated diverticulitis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Secondary ‐ Adverse events · Patients with acute uncomplicated diverticulitis

The review found no eligible studies for this question.

1 finding from 1 review