Cochrane · systematic review · CD012125
Corticosteroids for septic arthritis in children
Delgado‐Noguera, MF, Forero Delgadillo, JM, Franco, AA, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
MusculoskeletalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 28.6%Very low 0 · 0%Low 5 · 71.4%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Corticosteroids (dexamethasone) compared to placebo for septic arthritis in children
Population: septic arthritis in children taking antibiotics
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain ‐ absence of pain at 12 months Corticosteroids (dexamethasone) vs placebo | RR 1.33 [1.03, 1.72] | 1 study · 49 participants | Low Downgraded: risk of bias, imprecision |
Activities of daily living Corticosteroids (dexamethasone) vs placebo | no estimate extracted | 0 studies · 0 participants | Ungraded |
Number of participants with normal physical joint function ‐ normal function at 12 months of Corticosteroids (dexamethasone) vs placebo | RR 1.32 [1.12, 1.57] | 1 study · 100 participants | Low Downgraded: risk of bias, imprecision |
Number of days of antibiotic treatment ‐ number of days of intravenous antibiotic treatment Corticosteroids (dexamethasone) vs placebo | MD 2.77 | 2 studies · 149 participants | Low Downgraded: risk of bias, imprecision |
Length of hospital stay Corticosteroids (dexamethasone) vs placebo | no estimate extracted | 0 studies · 0 participants | Ungraded |
Total adverse events at 12 months Corticosteroids (dexamethasone) vs placebo | no estimate extracted | 1 study · 49 participants | Low Downgraded: risk of bias, imprecision |
Serious adverse events at 12 months Corticosteroids (dexamethasone) vs placebo | no estimate extracted | 1 study · 49 participants | Low Downgraded: risk of bias, imprecision |