Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

458 questions · 473 findings · 205 reviews

No studies found 128 · 27.1%GRADE not reported 49 · 10.4%Very low 142 · 30%Low 106 · 22.4%Moderate 36 · 7.6%High 12 · 2.5%

Lay health worker‐led interventions for adult patients with harmful or hazardous alcohol or substance use vs enhanced usual care

Adverse events ‐ death in past 12 months (RR > 1 denotes higher risk of death) · adult patients with harmful or hazardous alcohol or substance use

It is very uncertain whether lay health worker‐led interventions for adult patients with harmful… changes adverse events ‐ deaths (RR < 1 denotes lower risk) compared with enhanced usual care (very low certainty).

1 finding from 1 review

Active exercise regimen vs an immobilisation regimen following surgery

Adverse events requiring (or indicated for) surgery · participants undergoing rehabilitation following surgery for flexor tendon injuries of the handa

It is very uncertain whether active exercise regimen changes adverse events requiring (or indicated for) surgery compared with an immobilisation regimen following surgery (very low certainty).

1 finding from 1 review

Place and hold exercise regimen vs controlled passive exercise regimen following surgery

Adverse events requiring (or indicated for) surgery · participants undergoing rehabilitation following surgery for flexor tendon injuries of the handa

It is very uncertain whether place and hold exercise regimen changes adverse events requiring (or indicated for) surgery compared with controlled passive exercise regimen following surgery (very low certainty).

1 finding from 1 review

Yoga vs exercise

Adverse events · patients with non‐specific chronic low back pain

Yoga showed no clear difference in adverse events compared with exercise (low certainty).

1 finding from 1 review

Body awareness interventions vs control

Adverse events · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

It is very uncertain whether body awareness interventions changes adverse events compared with any control (very low certainty).

1 finding from 1 review