Cochrane · systematic review · CD003586
Non‐pharmacological interventions for spatial neglect or inattention following stroke and other non‐progressive brain injury
Longley, V, Hazelton, C, Heal, C, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
57
current version
GRADE rated
24
No studies
32
Included studies
NR
No studies 32 · 56.1%Ungraded 1 · 1.8%Very low 24 · 42.1%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Visual interventions compared to any control for spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
Population: spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Primary outcome Visual interventions vs any control | no estimate extracted | NR | No studies |
Activities of daily living: effects persisting at least 1 month post intervention Visual interventions vs any control | no estimate extracted | 2 studies · 55 participants | Very low Downgraded: risk of bias |
Secondary outcomes Visual interventions vs any control | no estimate extracted | NR | No studies |
Activities of daily living: immediate effects Visual interventions vs any control | no estimate extracted | 3 studies · 75 participants | Very low Downgraded: risk of bias |
Neglect outcomes: effects persisting at least 1 month post intervention Visual interventions vs any control | SMD 0.14 | 5 studies · 98 participants | Very low Downgraded: risk of bias |
Neglect outcomes: immediate effects Visual interventions vs any control | SMD 0.08 | 7 studies · 142 participants | Very low Downgraded: risk of bias |
Adverse events Visual interventions vs any control | no estimate extracted | NR | No studies |
Prism adaptation training compared to any control for spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
Population: spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Primary outcome Prism adaptation training vs any control | no estimate extracted | NR | No studies |
Activities of daily living: effects persisting at least 1 month post intervention Prism adaptation training vs any control | no estimate extracted | 2 studies · 39 participants | Very low Downgraded: risk of bias |
Secondary outcomes Prism adaptation training vs any control | no estimate extracted | NR | No studies |
Activities of daily living: immediate effects Prism adaptation training vs any control | SMD 0.2 | 5 studies · 158 participants | Very low Downgraded: risk of bias |
Neglect outcomes: effects persisting at least 1 month post intervention Prism adaptation training vs any control | SMD 0.05 | 1 study · 16 participants | Very low Downgraded: risk of bias |
Neglect outcomes: immediate effects Prism adaptation training vs any control | SMD 0.28 | 5 studies · 154 participants | Very low Downgraded: risk of bias |
Adverse events Prism adaptation training vs any control | no estimate extracted | NR | No studies |
Body awareness interventions compared to any control for spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
Population: spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Primary outcome Body awareness interventions vs any control | no estimate extracted | NR | No studies |
Activities of daily living: effects persisting at least 1 month post intervention Body awareness interventions vs any control | SMD 0.61 | 5 studies · 125 participants | Very low Downgraded: risk of bias |
Secondary outcomes Body awareness interventions vs any control | no estimate extracted | NR | No studies |
Activities of daily living: immediate effects Body awareness interventions vs any control | SMD 0.26 | 7 studies · 221 participants | Very low Downgraded: risk of bias |
Neglect outcomes: effects persisting at least 1 month post intervention Body awareness interventions vs any control | SMD 0.36 | 5 studies · 125 participants | Very low Downgraded: risk of bias |
Neglect outcomes: immediate effects Body awareness interventions vs any control | SMD 0.16 | 10 studies · 311 participants | Very low Downgraded: risk of bias |
Adverse events Body awareness interventions vs any control | OR 0.36 [0.05, 2.6] | 2 studies · 130 participants | Very low Downgraded: risk of bias |
Mental function interventions compared to any control for spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
Population: spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Primary outcome Mental function interventions vs any control | no estimate extracted | NR | No studies |
Activities of daily living: effects persisting at least 1 month post intervention Mental function interventions vs any control | no estimate extracted | NR | No studies |
Secondary outcomes Mental function interventions vs any control | no estimate extracted | NR | No studies |
Activities of daily living: immediate effects Mental function interventions vs any control | SMD 0.32 | 1 study · 24 participants | Very low Downgraded: risk of bias |
Neglect outcomes: effects persisting at least 1 month post intervention Mental function interventions vs any control | no estimate extracted | NR | No studies |
Neglect outcomes: immediate effects Mental function interventions vs any control | SMD 0.1 | 3 studies · 60 participants | Very low Downgraded: risk of bias |
Adverse events Mental function interventions vs any control | no estimate extracted | NR | No studies |
Movement interventions compared to any control for spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
Population: spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Primary outcome Movement interventions vs any control | no estimate extracted | NR | No studies |
Activities of daily living: effects persisting at least 1 month post intervention Movement interventions vs any control | no estimate extracted | NR | No studies |
Secondary outcomes Movement interventions vs any control | no estimate extracted | NR | No studies |
Activities of daily living: immediate effects Movement interventions vs any control | SMD 0.57 | 3 studies · 75 participants | Very low Downgraded: risk of bias |
Neglect outcomes: effects persisting at least 1 month post intervention Movement interventions vs any control | no estimate extracted | NR | No studies |
Neglect outcomes: immediate effects Movement interventions vs any control | SMD 0.57 | 2 studies · 58 participants | Very low Downgraded: risk of bias |
Adverse events Movement interventions vs any control | no estimate extracted | NR | No studies |
NIBS compared to any control for spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
Population: spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Primary outcome NIBS vs any control | no estimate extracted | NR | No studies |
Activities of daily living: effects persisting at least 1 month post intervention NIBS vs any control | SMD 0.35 | 3 studies · 92 participants | Very low Downgraded: risk of bias |
Secondary outcomes NIBS vs any control | no estimate extracted | NR | No studies |
Activities of daily living: immediate effects NIBS vs any control | SMD 0.61 | 6 studies · 160 participants | Very low Downgraded: risk of bias |
Neglect outcomes: effects persisting at least 1 month post intervention NIBS vs any control | SMD 0.77 | 3 studies · 102 participants | Very low Downgraded: risk of bias |
Neglect outcomes: immediate effects NIBS vs any control | SMD 0.75 | 10 studies · 244 participants | Very low Downgraded: risk of bias |
Adverse events NIBS vs any control | no estimate extracted | 1 study · 24 participants | Ungraded |
CI: Confidence interval NIBS vs any control | no estimate extracted | NR | No studies |
Electrical stimulation compared to any control for spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
Population: spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Primary outcome Electrical stimulation vs any control | no estimate extracted | NR | No studies |
Activities of daily living: effects persisting at least 1 month post intervention Electrical stimulation vs any control | no estimate extracted | NR | No studies |
Secondary outcomes Electrical stimulation vs any control | no estimate extracted | NR | No studies |
Activities of daily living: immediate effects Electrical stimulation vs any control | no estimate extracted | NR | No studies |
Neglect outcomes: effects persisting at least 1 month post intervention Electrical stimulation vs any control | no estimate extracted | NR | No studies |
Neglect outcomes: immediate effects Electrical stimulation vs any control | SMD 0.99 | 2 studies · 60 participants | Very low Downgraded: risk of bias |
Adverse events Electrical stimulation vs any control | no estimate extracted | NR | No studies |
Acupuncture compared to any control for spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
Population: spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Primary outcome Acupuncture vs any control | no estimate extracted | NR | No studies |
Activities of daily living: effects persisting at least 1 month post intervention Acupuncture vs any control | no estimate extracted | NR | No studies |
Secondary outcomes Acupuncture vs any control | no estimate extracted | NR | No studies |
Activities of daily living: immediate effects Acupuncture vs any control | SMD 0.65 | 2 studies · 104 participants | Very low Downgraded: risk of bias |
Neglect outcomes: effects persisting at least 1 month post intervention Acupuncture vs any control | no estimate extracted | NR | No studies |
Neglect outcomes: immediate effects Acupuncture vs any control | SMD 0.57 | 2 studies · 104 participants | Very low Downgraded: risk of bias |
Adverse events Acupuncture vs any control | no estimate extracted | NR | No studies |