Cochrane · systematic review · CD011112

Therapeutic exercises for affecting post‐treatment swallowing in people treated for advanced‐stage head and neck cancers

Perry, A, Lee, SH, Cotton, S, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

ENTAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 8 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Therapeutic swallowing exercises compared with treatment as usual (TAU) for dysphagia in head and neck cancer patients

Population: adults with advanced head and neck cancer
6 questions
OutcomeEffectEvidenceStatus / GRADE
Swallowing function/efficiency Measured using a rating of oropharyngeal swallowing efficiency (OPSE) quantifying the interaction of the speed of bolus movement and safety/efficiency in clearing material from the oropharynx Dysphagia is defined as ...
Therapeutic swallowing exercises vs treatment
no estimate extracted1 study · 16 participantsVery low
Adverse event: Weight loss (> 10%) Change in nutritional status reflected by a patient's weight measured at 6 weeks post‐treatment
Therapeutic swallowing exercises vs treatment
RR 0.62 [0.22, 1.71]1 study · 27 participantsVery low
Adverse event: Weight loss (> 10%) Change in nutritional status reflected by a patient's weight during the study period 10 weeks post‐treatment
Therapeutic swallowing exercises vs treatment
no estimate extracted1 study · 55 participantsVery low
Adverse event: Weight change Patient's body weight 6 months before the start of treatment was retrieved from the patient's medical notes and "relative weight change" was calculated as the percentage weight change relative to the weight at week 0 6...
Therapeutic swallowing exercises vs treatment
MD 1.341 study · 120 participantsVery low
Aspiration Scored as present, trace or absent, for any consistency 5 months post‐treatment
Therapeutic swallowing exercises vs treatment
no estimate extracted1 study · 39 participantsVery low
Penetration Scored as present, trace or absent, for any consistency 5 months post‐treatment
Therapeutic swallowing exercises vs treatment
no estimate extracted1 study · 39 participantsVery low

Therapeutic swallowing exercises compared with sham intervention for dysphagia in head and neck cancer patients

Population: adults with advanced head and neck cancer
2 questions
OutcomeEffectEvidenceStatus / GRADE
Adverse events: Dysphagia‐related complications Occurrence of dysphagia‐related complications: pneumonia, dehydration, mucositis and oral yeast infection
Therapeutic swallowing exercises vs sham intervention
no estimate extracted1 study · 27 participantsVery low
Adverse event: Weight loss (> 10%) Change in nutritional status reflected by a patient's weight at 6 weeks after treatment
Therapeutic swallowing exercises vs sham intervention
RR 0.62 [0.22, 1.71]1 study · 27 participantsVery low