Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,228 questions · 1,245 findings · 383 reviews

No studies found 403 · 32.4%GRADE not reported 128 · 10.3%Very low 385 · 30.9%Low 232 · 18.6%Moderate 81 · 6.5%High 16 · 1.3%

Antibiotics vs placebo or no intervention

Non‐serious adverse events · farmworkers, soldiers, and people in endemic areas

It is very uncertain whether summary of findings table ‐ Antibiotics changes non‐serious adverse events compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Summary of findings: pioglitazone monotherapy vs no intervention

Serious adverse events (N) · people at increased risk for developing type 2 diabetes

Summary of findings: pioglitazone monotherapy showed no clear difference in serious adverse events (N) compared with no intervention (low certainty).

1 finding from 1 review

Acupuncture vs sham

Adverse events Self‐reported · patients with non‐specific chronic low back pain

Acupuncture showed no clear difference in adverse events Self‐reported compared with sham intervention (low certainty).

1 finding from 1 review

Fibrin‐based haemostatic agents vs placebo or no intervention

Serious adverse events Median · adults undergoing liver resection for cancer or benign disease

It is very uncertain whether fibrin‐based haemostatic agents changes serious adverse events Median compared with no intervention or placebo (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse events related to RIPC · patients undergoing a surgical intervention that induces kidney injury

The intervention showed no clear difference in adverse events related to RIPC (high certainty).

1 finding from 1 review