Cochrane · systematic review · CD013333
Tea tree oil for Demodex blepharitis
Savla, K, Le, JT, Pucker, AD · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 3 · 42.9%Very low 2 · 28.6%Low 2 · 28.6%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
No tea tree oil group compared to tea tree oil (intervention) group for Demodex blepharitis
Population: Demodex blepharitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mean change in number of Demodex mites per 8 eyelashes at 4–6 weeks No tea tree oil group vs tea tree oil (intervention) group | no estimate extracted | 3 studies · 215 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Mean change in participant‐reported change in symptoms at 4–6 weeks No tea tree oil group vs tea tree oil (intervention) group | no estimate extracted | 2 studies · 246 participants | Low Downgraded: risk of bias, inconsistency |
Participants with an improvement in visual acuity at 4–6 weeks No tea tree oil group vs tea tree oil (intervention) group | no estimate extracted | 1 study · 86 participants | Low Downgraded: risk of bias, inconsistency |
Mean change in (or mean) number of cylindrical dandruff at 4–6 weeks No tea tree oil group vs tea tree oil (intervention) group | no estimate extracted | 0 studies · 0 participants | Ungraded |
Proportion of participants with meibomian gland dysfunction at 4–6 weeks No tea tree oil group vs tea tree oil (intervention) group | no estimate extracted | 0 studies · 0 participants | Ungraded |
Proportion of participants experiencing conjunctival injection (redness) at 4–6 weeks No tea tree oil group vs tea tree oil (intervention) group | no estimate extracted | 0 studies · 0 participants | Ungraded |
Adverse events at 4‐6 weeks No tea tree oil group vs tea tree oil (intervention) group | no estimate extracted | 3 studies · 318 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |