Any adverse effects (e.g. hypervitaminosis A, as defined by the trialists) · preschool and school‐age children
Point‐of‐use fortification of foods with micronutrients powders (MNP) showed no clear difference in adverse effects (any, as defined by trialists) compared with no intervention or placebo (moderate certainty).
1 finding from 1 review
Anxiety (adverse effect, post‐intervention)
1 finding from 1 review
Adverse events associated with treatment · women during pregnancy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events associated with treatment · women during pregnancy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects (cataract development, choroidal detachment, new/iatrogenic breaks, postoperative proliferative vitreoretinopathy, postoperative increase in intraocular pressure, development of cystoid macular oedema, macular pucker, strabismus) a... · people with simple rhegmatogenous retinal detachments
Pars plana vitrectomy (PPV) may leads to higher adverse effects (cataract development, choroidal detachment,… compared with scleral buckling (low certainty).
1 finding from 1 review
Adverse effects sufficient to stop treatment · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate probably leads to higher adverse effects severe enough to stop treatment** compared with placebo (outcomes (moderate certainty).
1 finding from 1 review
Intervention not reported
Discontinuation of therapy due to adverse effects · patients in primary prevention of cardiovascular disease events
It is very uncertain whether the intervention changes discontinuation of therapy due to adverse effects (very low certainty).
1 finding from 1 review
Diarrhoea · women with obesity during pregnancy
Metformin leads to higher adverse effects associated with the treatment: diarrhoea compared with placebo (high certainty).
1 finding from 1 review
Gastrointestinal adverse events · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure ulcers
It is very uncertain whether summary of findings table ‐ Energy, protein and micronutrients changes side effects: at least one adverse gastrointestinal event compared with standard diet (very low certainty).
1 finding from 1 review
Gastrointestinal adverse events · residents of long‐term care (≥ 65 years) with pressure ulcers; inpatients with pressure ulcers
It is very uncertain whether summary of findings table ‐ Protein, arginine, zinc and antioxidants changes side effects: at least one adverse gastrointestinal event compared with standard diet or placebo (very low certainty).
1 finding from 1 review
Gastrointestinal adverse events · malnourished patients with pressure ulcers
It is very uncertain whether summary of findings table ‐ Arginine and micronutrients changes side effects: at least one adverse gastrointestinal event compared with standard diet (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · adults (aged 18 years+) with depression in bipolar disorder
1 finding from 1 review
Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
In 1 study, people complained about a transient bitter taste associated with SDF (with no associated data), with no other adverse effects. In another study, there were no adverse effects. No studies reported this…
2 studies · 336 participants
Very low
Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
In 1 study, 115 of 118 children had black stains on teeth treated with SDF; there were no other adverse effects or allergic reactions. In 1 study, the rate of adverse effects reported by caregiver and person who…
3 studies · 482 participants
Very low
Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
Ruff 2022 reported that there were no adverse events during the study period; adverse events were not defined by the study authors. Assumed data available for 1398 participants.
1 study · 1398 participants
Very low
Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
Gao 2019 noted that "arrested lesions were stained black" (reported with no associated data). No other adverse effects observed, and no reports from parents of systemic disease.
1 study · 1070 participants
Very low
Intervention not reported
Adverse effects · people with healed venous leg ulcers
1 finding from 1 review
no estimate extracted
1995 participants
GRADE not reported
Adverse effects · people undergoing gastrointestinal surgery
1 finding from 1 review