Question · asked by 1 review

Ketamine vs midazolam: Withdrawals due to adverse events

Population
adults (aged 18 years+) with depression in bipolar disorder
Intervention
Ketamine
Comparison
midazolam
Outcome
Withdrawals due to adverse events

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Ketamine vs midazolam
Acceptability: dropouts due to adverse effects at 24 hours · adults (aged 18 years+) with depression in bipolar disorder
Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder (2021) · Cochrane Headline outcomes only
no estimate extracted1 study · 16 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder
2021 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.