Surgery vs no surgery
SAEs · participants with obesity
1 finding from 1 review
- no estimate extracted4 studies · 438 participantsVery low
Findings
What do systematic reviews say?
48 questions · 53 findings · 23 reviews
No studies found 19 · 35.8%GRADE not reported 4 · 7.5%Very low 24 · 45.3%Low 3 · 5.7%Moderate 3 · 5.7%High 0 · 0%
Surgery vs non‐surgical treatment
Adverse events · people with full‐thickness rotator cuff tears
1 finding from 1 review
- no estimate extracted1 study · 103 participantsVery low
Surgery vs non‐surgical treatment
Serious adverse events · people with full‐thickness rotator cuff tears
1 finding from 1 review
- no estimate extractedStudies not reportedVery low
Surgery vs radiofrequency ablation
Serious adverse events (number of events) · people with early‐ or very early‐stage hepatocellular carcinoma eligible for surgery
Surgery may leads to higher serious adverse events (number of events) compared with radiofrequency ablation (low certainty).
1 finding from 1 review
- Management of people with early‐ or very early‐stage hepatocellular carcinoma 2017 · Cochrane Headline outcomes onlyRate ratio 7.02 [2.29, 21.46]2 studies · 391 participantsLow
Surgery vs radiofrequency ablation
Serious adverse events (number of participants) · people with early‐ or very early‐stage hepatocellular carcinoma eligible for surgery
Surgery may leads to higher serious adverse events (number of participants) compared with radiofrequency ablation (low certainty).
1 finding from 1 review
- Management of people with early‐ or very early‐stage hepatocellular carcinoma 2017 · Cochrane Headline outcomes onlyOR 17.96 [2.28, 141.6]1 study · 120 participantsLow
Surgery vs oral medication
Adverse events at 4 months · women with heavy menstrual bleeding
Surgery probably leads to lower adverse events at 4 months compared with oral medication (moderate certainty).
1 finding from 1 review
- RR 0.26 [0.15, 0.46]1 study · 186 participantsModerate
Prophylactic plasma transfusion before surgery/invasive procedures vs no prophylactic plasma transfusion before surgery/invasive procedures (colloid, crystalloid, placebo, or no treatment)
Serious adverse events measured by surgery or procedure‐related complications within 30 days ‐ not reported · patients undergoing non‐cardiac surgery/invasive procedures
The review found no eligible studies for this question.
1 finding from 1 review
- Prophylactic plasma transfusion for patients without inherited bleeding disorders or anticoagulant use undergoing… 2019 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Day‐surgery vs overnight stay surgery
Serious adverse events · patients with laparoscopic cholecystectomy.
It is very uncertain whether day‐surgery changes serious adverse events compared with overnight stay surgery (very low certainty).
1 finding from 1 review
- Day‐surgery versus overnight stay surgery for laparoscopic cholecystectomy 2013 · Cochrane Headline outcomes onlyRate Ratio 3.24 [0.74, 14.09]4 studies · 391 participantsVery low
Surgery vs LNG‐IUS
Proportion of women with adverse events Endometrial ablation versus LNG‐IUS. At one year · women with heavy menstrual bleeding
Surgery probably leads to lower proportion of women with adverse events Endometrial ablation versus… compared with LNG‐IUS (moderate certainty).
1 finding from 1 review
- RR 0.51 [0.36, 0.74]3 studies · 201 participantsModerate
Surgery with excision of failed tape vs surgery without excision of tape
Adverse events · women with recurrent stress urinary incontinence after failed minimally invasive midurethral tape surgery
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for treating recurrent stress urinary incontinence after failed minimally invasive synthetic midurethral… 2019 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Prophylactic platelet transfusion prior to surgery vs no prophylactic platelet transfusion prior to surgery
Serious adverse events (surgery‐related adverse effects within 30 days) · people with a low platelet count
1 finding from 1 review
- Prophylactic platelet transfusions prior to surgery for people with a low platelet count 2018 · Cochrane Headline outcomes onlyno estimate extracted1 study · 64 participantsVery low
Surgery vs preoperative pharmacological therapy and surgery
Adverse events · adults with growth‐hormone secreting pituitary adenomas
It is very uncertain whether surgery alone changes adverse events compared with preoperative pharmacological therapy and surgery (very low certainty).
1 finding from 1 review
- Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting pituitary… 2024 · Cochrane Headline outcomes onlyRR 1.23 [0.7, 2.03]5 studies · 267 participantsVery low
Surgery vs Radiotherapy alone
Adverse events associated with treatment · Adults with oropharyngeal cancer
1 finding from 1 review
- Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomesAdverse events: grade 2+ treatment-related events similar (31/34 radiotherapy vs 33/34 surgery; RR 0.94, 0.83 to 1.06); more hearing loss/neutropenia/constipation/tinnitus with radiotherapy, more oral bleeding/trismus…1 study · 68 participantsVery low
Neoadjuvant chemotherapy prior to interval surgery (NACT) vs surgery followed by chemotherapy (PDS)
Surgically‐related severe adverse effects (grade 3+) ‐ postoperative G3+ events (within 30 days of surgery) · women with advanced ovarian epithelial cancer
Neoadjuvant chemotherapy prior to interval surgery (NACT) probably leads to lower surgically‐related severe adverse effects (grade 3+) ‐ postoperative… compared with surgery followed by chemotherapy (PDS) (moderate certainty).
1 finding from 1 review
- Neoadjuvant chemotherapy before surgery versus surgery followed by chemotherapy for initial treatment in advanced… 2021 · Cochrane Headline outcomes onlyRR 0.22 [0.13, 0.38]2 studies · 435 participantsModerate
Prophylactic plasma transfusion before surgery/invasive procedures vs alternative haemostatic agents
Serious adverse events measured by surgery or procedure‐related complications within 30 days ‐ not reported · patients undergoing non‐cardiac surgery/invasive procedures
The review found no eligible studies for this question.
1 finding from 1 review
- Prophylactic plasma transfusion for patients without inherited bleeding disorders or anticoagulant use undergoing… 2019 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Prism adaptation test with eye muscle surgery vs eye muscle surgery alone
Minor adverse events Defined as any adverse event within 8 weeks of surgery that does not require further intervention · people with intermittent exotropia, aged 5 to 49 years
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Endoscopic surgery vs open surgery
Adverse events (infection, dysaesthesia) · patients with trigger finger
It is very uncertain whether endoscopic surgery changes adverse events (infection, dysaesthesia) compared with open surgery (very low certainty).
1 finding from 1 review
- RR 2.74 [0.74, 10.06]1 study · 231 participantsVery low
Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery
Adverse events · people with single or solitary brain metastasis
It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes adverse events compared with stereotactic radiosurgery (very low certainty).
1 finding from 1 review
- Surgery versus stereotactic radiotherapy for people with single or solitary brain metastasis 2018 · Cochrane Headline outcomes onlyRR 0.31 [0.07, 1.44]1 study · 64 participantsVery low
Surgery vs Pharmacological therapy
Adverse events · adults with growth‐hormone secreting pituitary adenomas
It is very uncertain whether surgery alone changes adverse events compared with pharmacological therapy alone (very low certainty).
1 finding from 1 review
- Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting pituitary… 2024 · Cochrane Headline outcomes onlyRR 0.09 [0.01, 1.47]1 study · 22 participantsVery low
iMRI image‐guided surgery vs surgery
Adverse events · high‐grade glioma
The review found no eligible studies for this question.
2 findings from 2 reviews · compare the 2 reviews
- Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
- Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found