Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

152 questions · 163 findings · 80 reviews

No studies found 69 · 42.3%GRADE not reported 16 · 9.8%Very low 46 · 28.2%Low 23 · 14.1%Moderate 6 · 3.7%High 3 · 1.8%

Lay health worker‐led interventions for adult patients with harmful or hazardous alcohol or substance use vs enhanced usual care

Adverse events ‐ death in past 12 months (RR > 1 denotes higher risk of death) · adult patients with harmful or hazardous alcohol or substance use

It is very uncertain whether lay health worker‐led interventions for adult patients with harmful… changes adverse events ‐ deaths (RR < 1 denotes lower risk) compared with enhanced usual care (very low certainty).

1 finding from 1 review

Interventions for involving older patients with multi‐morbidity in decision‐making about their health care vs usual care

Adverse event** Less patient involvement as a result of the intervention Not measured · older patients with multi‐morbidity

The review found no eligible studies for this question.

1 finding from 1 review

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs conservative interventions

Serious adverse events · Children and adolescents with femoral shaft fractures

Surgical interventions may leads to higher serious adverse events compared with conservative interventions (low certainty).

1 finding from 1 review