Cochrane · systematic review · CD006047

Household interventions for secondary prevention of domestic lead exposure in children

Nussbaumer-Streit, B, Mayr, V, Dobrescu, AI, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
15
current version
GRADE rated
8
No studies
7
Included studies
NR
No studies 7 · 46.7%Ungraded 0 · 0%Very low 4 · 26.7%Low 1 · 6.7%Moderate 3 · 20%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 4 versions

Education interventions versus no intervention for preventing domestic lead exposure in children

Population: children (aged 0–2 years)
4 questions
OutcomeEffectEvidenceStatus / GRADE
Cognitive and neurobehavioural outcomes
Education interventions vs no intervention
no estimate extractedNRNo studies
Adverse events
Education interventions vs no intervention
no estimate extractedNRNo studies
Blood lead levels (continuous)Blood lead levels after intervention Scale: 0–30
Education interventions vs no intervention
no estimate extracted5 studies · 815 participantsModerate
Downgraded: risk of bias, imprecision
Household dust: hard floor dust lead levels (continuous)Floor dust lead levels Scale: 0–40
Education interventions vs no intervention
no estimate extracted2 studies · 318 participantsModerate
Downgraded: imprecision

Environmental interventions versus no intervention for preventing domestic lead exposure in children

Population: children (aged 0–6 years)
7 questions
OutcomeEffectEvidenceStatus / GRADE
Cognitive and neurobehavioural outcomes Scale Wechsler IQ: BRIEF:
Environmental interventions vs no intervention
no estimate extracted1 study · 224 participantsLow
Downgraded: risk of bias, imprecision
Adverse events
Environmental interventions vs no intervention
no estimate extracted1 study · 355 participantsVery low
Downgraded: imprecision
Blood lead levels (continuous)Blood lead level at end of duration Scale: 0–30
Environmental interventions vs no intervention
no estimate extracted4 studies · 565 participantsModerate
Downgraded: imprecision
Household dust: floor dust lead levels
Environmental interventions vs no intervention
no estimate extractedNRNo studies
Cognitive and neurobehavioural outcomes
Environmental interventions vs no intervention
no estimate extractedNRNo studies
Adverse events
Environmental interventions vs no intervention
no estimate extractedNRNo studies
Blood lead levels (continuous)Blood lead level at end of duration Scale: 0–30
Environmental interventions vs no intervention
no estimate extracted2 studies · 378 participantsVery low
Downgraded: risk of bias, imprecision

Combination interventions versus standard education for preventing domestic lead exposure in children

Population: children (aged 0–4 years)
4 questions
OutcomeEffectEvidenceStatus / GRADE
Cognitive and neurobehavioural outcomes
Combination interventions vs standard education
no estimate extractedNRNo studies
Adverse events
Combination interventions vs standard education
no estimate extractedNRNo studies
Blood lead levels (continuous)Blood lead level at end of duration Scale: 0–30
Combination interventions vs standard education
no estimate extracted4 studies · 426 participantsVery low
Downgraded: risk of bias, imprecision
Household dust: floor dust lead levels
Combination interventions vs standard education
no estimate extracted2 studies · 336 participantsVery low
Downgraded: risk of bias, imprecision