It is very uncertain whether late (seven days or more following birth) higher changes mortality (latest time reported up to hospital discharge) compared with lower sodium intake (very low certainty).
Early (less than seven days following birth) higher showed no clear difference in mortality (latest time reported up to hospital discharge) compared with lower sodium intake (low certainty).
High showed no clear difference in mortality compared with non‐high (medium or low) dose regimen (low certainty).
It is very uncertain whether high changes all‐cause mortality compared with low blood pressure target (very low certainty).
Highest showed no clear difference in cancer mortality risk No. of participants: 17,448 (1 RCT) compared with lowest selenium exposure (high certainty).
Higher showed no clear difference in mortality to hospital discharge compared with lower amino acid intake (low certainty).
It is very uncertain whether higher changes all‐cause mortality: range 1 mo to 1 y compared with lower FiO2 or targets of arterial oxygenation (very low certainty).
High showed no clear difference in all‐cause mortality – deaths compared with low long‐chain omega‐3 fats (high certainty).
High showed no clear difference in all‐cause mortality – deaths compared with low alpha‐linolenic acid omega‐3 fats (moderate certainty).
The review found no eligible studies for this question.
High showed no clear difference in coronary heart disease mortality – CHD deaths compared with low alpha‐linolenic acid omega‐3 fats (moderate certainty).
High showed no clear difference in coronary heart disease mortality – CHD deaths compared with low long‐chain omega‐3 fats (low certainty).
The review found no eligible studies for this question.
High showed no clear difference in cardiovascular mortality – cardiovascular deaths compared with low alpha‐linolenic acid omega‐3 fats (moderate certainty).
High probably leads to lower cardiovascular mortality – cardiovascular deaths compared with low long‐chain omega‐3 fats (moderate certainty).
High levels of PEEP showed no clear difference in mortality before hospital discharge compared with low levels of PEEP (moderate certainty).
Each additional lost tooth was associated with a multivariable-adjusted HR of 1.02 (95% CI 1.01 to 1.03) for all-cause mortality (11 studies, I2=89%), statistically significant; GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).