Early ART may leads to higher all‐cause mortality at 6 to 12 months compared with delayed ART initiation (low certainty).
Early ART showed no clear difference in cryptococcal meningitis relapse compared with delayed ART initiation (low certainty).
It is very uncertain whether early ART changes cryptococcal IRIS compared with delayed ART initiation (very low certainty).
It is very uncertain whether early ART changes HIV virological suppression at 6 months (viral load < 400 copies/mL) compared with delayed ART initiation (very low certainty).
Early ART probably leads to lower death compared with standard or deferred ART (CD4 <= 200 or CD4 <= 250 cells/µl) (moderate certainty).
Early ART showed no clear difference in tuberculosis compared with standard or deferred ART (CD4 <= 200 or CD4 <= 250 cells/µl) (moderate certainty).
Early ART showed no clear difference in disease progression measured by opportunistic disease Opportunistic… compared with standard or deferred ART (CD4 <= 200 or CD4 <= 250 cells/µl) (low certainty).
Early may leads to higher heart failure compared with deferred AST (low certainty).
Early showed no clear difference in seizure relapse rate in people with partial epilepsy by time of… compared with late AED withdrawal (low certainty).
It is very uncertain whether early changes overall morbidity Median compared with delayed open or laparoscopic appendicectomy (very low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
It is very uncertain whether early changes total length of hospital stay (days) compared with delayed laparoscopic appendicectomy (very low certainty).
The review found no eligible studies for this question.
It is very uncertain whether early changes wound infection Median compared with delayed open or laparoscopic appendicectomy (very low certainty).
It is very uncertain whether early changes abdominal abscess Median compared with delayed open or laparoscopic appendicectomy (very low certainty).
It is very uncertain whether early changes faecal fistula Median compared with delayed open or laparoscopic appendicectomy (very low certainty).
It is very uncertain whether early changes total length of hospital stay (days) compared with delayed open or laparoscopic appendicectomy (very low certainty).