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Evidence found and GRADE certainty

8 questions · 8 findings · 4 reviews

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No studies found 1 · 12.5%GRADE not reported 3 · 37.5%Very low 1 · 12.5%Low 2 · 25%Moderate 1 · 12.5%High 0 · 0%

Chlorhexidine vs povidone‐iodine

All‐cause mortality ‐ Chlorhexidine in alcohol versus povidone‐iodine in aqueous solution Clinical assessment · patients with a central venous catheter

Chlorhexidine showed no clear difference in all‐cause mortality ‐ Chlorhexidine in alcohol versus… compared with povidone‐iodine (low certainty).

1 finding from 1 review

Chlorhexidine vs povidone‐iodine

All‐cause mortality ‐ Chlorhexidine in aqueous solution versus povidone‐iodine in aqueous solution Clinical assessment · patients with a central venous catheter

Chlorhexidine showed no clear difference in all‐cause mortality ‐ Chlorhexidine in aqueous solution versus… compared with povidone‐iodine (low certainty).

1 finding from 1 review

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

All‐cause mortality · Critically ill patients (adults and children) receiving mechanical ventilation in ICU

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care showed no clear difference in mortality compared with placebo or usual care (moderate certainty).

1 finding from 1 review

Bathing of the critically ill with chlorhexidine vs bathing with soap and water or non‐antimicrobial washcloths

Mortality (ICU, hospital) (days) · critically ill patients

It is very uncertain whether bathing of the critically ill with chlorhexidine changes mortality Data collected (where reported) in hospital, in the ICU,… compared with bathing with soap and water or non‐antimicrobial washcloths (very low certainty).

1 finding from 1 review