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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

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Intervention or exposure

Comparison

Outcome

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Review versions

26 questions in 11 reviews · Tobacco Addiction

current versions

No studies 26 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Question	Effect	Evidence	Status / GRADE
Cytisine vs varenicline Neuropsychiatric SAEs · people who smoke tobacco Nicotine receptor partial agonists for smoking cessation (2023) · Cochrane	no estimate extracted	NR	No studies
Cytisine vs varenicline Cardiac SAEs · people who smoke tobacco Nicotine receptor partial agonists for smoking cessation (2023) · Cochrane	no estimate extracted	NR	No studies
Cytisine vs nicotine replacement therapy Neuropsychiatric SAEs · people who smoke tobacco Nicotine receptor partial agonists for smoking cessation (2023) · Cochrane	no estimate extracted	NR	No studies
Cytisine vs nicotine replacement therapy Cardiac SAEs · people who smoke tobacco Nicotine receptor partial agonists for smoking cessation (2023) · Cochrane	no estimate extracted	NR	No studies
Cytisine vs placebo or no medication Neuropsychiatric SAEs (cytisine vs placebo or no medication) · people who smoke tobacco Nicotine receptor partial agonists for smoking cessation (2023) · Cochrane	no estimate extracted	NR	No studies
Cytisine vs placebo or no medication Cardiac SAEs (cytisine vs placebo or no medication) · people who smoke tobacco Nicotine receptor partial agonists for smoking cessation (2023) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Component · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC)… Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network… (2023) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Component · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC)… Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network… (2023) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Non‐nicotine/placebo EC · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC)… Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network… (2023) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Nortriptyline · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC)… Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network… (2023) · Cochrane	no estimate extracted	NR	No studies
Heated tobacco use vs snus use Smoking cessation – not measured · people who smoke Heated tobacco products for smoking cessation and reducing smoking prevalence (2022) · Cochrane	no estimate extracted	NR	No studies
Heated tobacco use vs abstinence from tobacco Smoking cessation – not measured · people who smoke Heated tobacco products for smoking cessation and reducing smoking prevalence (2022) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Test Accuracy · : Serum or plasma ferritin concentration as an index of iron deficiency and overload (2021) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Test Accuracy Serum or plasma ferritin concentration as an index of iron deficiency and overload (2021) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Test Accuracy · : Serum or plasma ferritin concentration as an index of iron deficiency and overload (2021) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Test Accuracy Serum or plasma ferritin concentration as an index of iron deficiency and overload (2021) · Cochrane	no estimate extracted	NR	No studies
Bupropion vs control Miscarriage and spontaneous abortion · pregnant women who smoke Pharmacological interventions for promoting smoking cessation during pregnancy (2020) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Telephone counselling · people who smoke and are involved in the care of young children (birth to 12 years of age) Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke (2018) · Cochrane	no estimate extracted	NR	No studies
Group‐format behavioural programmes vs alternative support Outcome: Smoking cessation assessed at least 6 months after start of treatment, based on self‐report, ± biochemical validation of abstinence · People who smoke Group behaviour therapy programmes for smoking cessation (2017) · Cochrane	no estimate extracted	NR	No studies
Behavioural interventions vs minimal control Comparisons and outcomes1 · young people Tobacco cessation interventions for young people (2017) · Cochrane	no estimate extracted	NR	No studies
Pharmacological interventions vs placebo Comparisons and outcomes · young people Tobacco cessation interventions for young people (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Outcomes1 · adults who want to stop smoking Internet‐based interventions for smoking cessation (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Uptake ‐ not measured · General population for prevalence outcomes. Adult smokers for tobacco consumption outcomes. Tobacco packaging design for reducing tobacco use (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Relapse ‐ not measured · General population for prevalence outcomes. Adult smokers for tobacco consumption outcomes. Tobacco packaging design for reducing tobacco use (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Cessation ‐ not measured · General population for prevalence outcomes. Adult smokers for tobacco consumption outcomes. Tobacco packaging design for reducing tobacco use (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Evidence of immunologic tolerance · adults with food allergy to fruits Immunotherapy (oral and sublingual) for food allergy to fruits (2015) · Cochrane	no estimate extracted	NR	No studies